Metabolism of propionic acid to a novel acyl-coenzyme A thioester by mammalian cell lines and platelets

Metabolism of propionate involves the activated acyl-thioester propionyl-CoA intermediate. We employed LC-MS/MS, LC-selected reaction monitoring/MS, and LC-high-resolution MS to investigate metabolism of propionate to acyl-CoA intermediates. We discovered that propionyl-CoA can serve as a precursor...

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Bibliographische Detailangaben
Veröffentlicht in:J Lipid Res
Hauptverfasser: Snyder, Nathaniel W., Basu, Sankha S., Worth, Andrew J., Mesaros, Clementina, Blair, Ian A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274062/
https://ncbi.nlm.nih.gov/pubmed/25424005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M055384
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