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Impact of a High-fat Diet on Tissue Acyl-CoA and Histone Acetylation Levels

Cellular metabolism dynamically regulates the epigenome via availability of the metabolite substrates of chromatin-modifying enzymes. The impact of diet on the metabolism-epigenome axis is poorly understood but could alter gene expression and influence metabolic health. ATP citrate-lyase produces ac...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Carrer, Alessandro, Parris, Joshua L. D., Trefely, Sophie, Henry, Ryan A., Montgomery, David C., Torres, AnnMarie, Viola, John M., Kuo, Yin-Ming, Blair, Ian A., Meier, Jordan L., Andrews, Andrew J., Snyder, Nathaniel W., Wellen, Kathryn E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336165/
https://ncbi.nlm.nih.gov/pubmed/28077572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.750620
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