Acetyl-CoA metabolism supports multi-step pancreatic tumorigenesis

Pancreatic ductal adenocarcinoma (PDA) has a poor prognosis, and new strategies for prevention and treatment are urgently needed. We previously reported that histone H4 acetylation is elevated in pancreatic acinar cells harboring Kras mutations prior to the appearance of premalignant lesions. Since...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cancer Discov
Main Authors: Carrer, Alessandro, Trefely, Sophie, Zhao, Steven, Campbell, Sydney L., Norgard, Robert J., Schulz, Kollin C., Sidoli, Simone, Parris, Joshua L. D., Affronti, Hayley C., Sivanand, Sharanya, Egolf, Shaun, Sela, Yogev, Trizzino, Marco, Gardini, Alessandro, Garcia, Benjamin A., Snyder, Nathaniel W., Stanger, Ben Z., Wellen, Kathryn E.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643997/
https://ncbi.nlm.nih.gov/pubmed/30626590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-18-0567
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares