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Metabolic Regulation of Histone Acetyltransferases by Endogenous Acyl-CoA Cofactors

The finding that chromatin modifications are sensitive to changes in cellular cofactor levels potentially links altered tumor cell metabolism and gene expression. However, the specific enzymes and metabolites that connect these two processes remain obscure. Characterizing these metabolic-epigenetic...

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Detalhes bibliográficos
Publicado no:Chem Biol
Main Authors: Montgomery, David C., Sorum, Alexander W., Guasch, Laura, Nicklaus, Marc C., Meier, Jordan L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546520/
https://ncbi.nlm.nih.gov/pubmed/26190825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.06.015
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