CCR5 Inhibitors and HIV-1 Infection

von Latinovic, Olga S., Reitz, Marvin, Heredia, Alonso
Veröffentlicht in J AIDS HIV Treat (2019)

Pharmacotherapy of HIV-1 Infection: Focus on CCR5 Antagonist Maraviroc

von Latinovic, Olga, Kuruppu, Janaki, Davis, Charles, Le, Nhut, Heredia, Alonso
Veröffentlicht 2009

A novel small-molecule inhibitor of HIV-1 entry

von Heredia, Alonso, Latinovic, Olga S, Barbault, Florent, de Leeuw, Erik PH
Veröffentlicht in Drug Des Devel Ther (2015)

Use of Humanized Mouse Models for Studying HIV-1 Infection, Pathogenesis and Persistence

von Weichseldorfer, Matthew, Heredia, Alonso, Reitz, Marvin, Bryant, Joseph L., Latinovic, Olga S.
Veröffentlicht in J AIDS HIV Treat (2020)

Binding of fusion protein FLSC IgG1 to CCR5 is enhanced by CCR5 antagonist Maraviroc

von Latinovic, Olga, Schneider, Kate, Szmacinski, Henryk, Lakowicz, Joseph R., Heredia, Alonso, Redfield, Robert R.
Veröffentlicht in Antiviral Res (2014)

An Alteration of Human Immunodeficiency Virus gp41 Leads to Reduced CCR5 Dependence and CD4 Independence

von Taylor, Brian M., Foulke, J. Scott, Flinko, Robin, Heredia, Alonso, DeVico, Anthony, Reitz, Marvin
Veröffentlicht 2008

Reduction of CCR5 with low-dose rapamycin enhances the antiviral activity of vicriviroc against both sensitive and drug-resistant HIV-1

von Heredia, Alonso, Latinovic, Olga, Gallo, Robert C., Melikyan, Gregory, Reitz, Marv, Le, Nhut, Redfield, Robert R.
Veröffentlicht 2008

Synergistic Inhibition of R5 HIV-1 by Maraviroc and CCR5 Antibody HGS004 in Primary Cells: Implications for Treatment and Prevention

von LATINOVIC, OLGA, LE, NHUT, REITZ, MARVIN, PAL, RANAJIT, DEVICO, ANTHONY, FOULKE, JAMES S., REDFIELD, ROBERT R., HEREDIA, ALONSO
Veröffentlicht 2011

CCR5 antibodies HGS004 and HGS101 preferentially inhibit drug-bound CCR5 infection and restore drug sensitivity of Maraviroc-resistant HIV-1 in primary cells

von Latinovic, Olga, Reitz, Marvin, Le, Nhut M., Foulke, James S., Fätkenheuer, Gerd, Lehmann, Clara, Redfield, Robert R., Heredia, Alonso
Veröffentlicht 2011

Induction of G(1) cycle arrest in T lymphocytes results in increased extracellular levels of β-chemokines: A strategy to inhibit R5 HIV-1

von Heredia, Alonso, Davis, Charles, Amoroso, Anthony, Dominique, Joyelle K., Le, Nhut, Klingebiel, Erin, Reardon, Elise, Zella, Davide, Redfield, Robert R.
Veröffentlicht 2003

Indirubin 3′-Monoxime, from a Chinese Traditional Herbal Formula, Suppresses Viremia in Humanized Mice Infected with Multidrug-Resistant HIV

von Heredia, Alonso, Natesan, Senthilkumar, Le, Nhut M., Medina-Moreno, Sandra, Zapata, Juan C., Reitz, Marvin, Bryant, Joseph, Redfield, Robert R.
Veröffentlicht 2014

Enzymatic glycosylation of triazole-linked GlcNAc/Glc-peptides. Synthesis, stability, and anti-HIV activity of triazole-linked HIV-1 gp41 glycopeptide C34

von Huang, Wei, Groothuys, Stan, Heredia, Alonso, Kuijpers, Brian H.M., Rutjes, Floris P.J.T., van Delft, Floris L., Wang, Lai-Xi
Veröffentlicht 2009

Targeting of the Purine Biosynthesis Host Cell Pathway Enhances the Activity of Tenofovir Against Sensitive and Drug-Resistant HIV-1

von Heredia, Alonso, Davis, Charles E., Reitz, Marvin S., Le, Nhut M., Wainberg, Mark A., Foulke, James S., Wang, Lai-Xi, Redfield, Robert R.
Veröffentlicht 2013

Targeting of CDK9 with indirubin 3’-monoxime safely and durably reduces HIV viremia in chronically infected humanized mice

von Medina-Moreno, Sandra, Dowling, Thomas C., Zapata, Juan C., Le, Nhut M., Sausville, Edward, Bryant, Joseph, Redfield, Robert R., Heredia, Alonso
Veröffentlicht in PLoS One (2017)

Rapamycin Reduces CCR5 Density Levels on CD4 T Cells, and This Effect Results in Potentiation of Enfuvirtide (T-20) against R5 Strains of Human Immunodeficiency Virus Type 1 In Vit...

von Heredia, Alonso, Gilliam, Bruce, Latinovic, Olga, Le, Nhut, Bamba, Douty, DeVico, Anthony, Melikyan, Gregory B., Gallo, Robert C., Redfield, Robert R.
Veröffentlicht 2007

Targeting of mTOR catalytic site inhibits multiple steps of the HIV-1 lifecycle and suppresses HIV-1 viremia in humanized mice

von Heredia, Alonso, Le, Nhut, Gartenhaus, Ronald B., Sausville, Edward, Medina-Moreno, Sandra, Zapata, Juan C., Davis, Charles, Gallo, Robert C., Redfield, Robert R.
Veröffentlicht in Proc Natl Acad Sci U S A (2015)

Targeting Host Nucleotide Biosynthesis with Resveratrol Inhibits Emtricitabine (FTC)-resistant HIV-1

von Heredia, Alonso, Davis, Charles, Amin, Mohammed N, Le, Nhut M, Wainberg, Mark A, Oliveira, Maureen, Deeks, Steven G, Wang, Lai-Xi, Redfield, Robert R
Veröffentlicht in AIDS (2014)

Monotherapy with either dolutegravir or raltegravir fails to durably suppress HIV viraemia in humanized mice

von Heredia, Alonso, Hassounah, Said, Medina-Moreno, Sandra, Zapata, Juan C., Le, Nhut M., Han, Yingshan, Foulke, James S., Davis, Charles, Bryant, Joseph, Redfield, Robert R., Wainberg, Mark A.
Veröffentlicht in J Antimicrob Chemother (2017)

Disparate Effects of Cytotoxic Chemotherapy on the Antiviral Activity of Antiretroviral Therapy: Implications for Treatments of HIV-Infected Cancer Patients

von Medina-Moreno, Sandra, Zapata, Juan C, Cottrell, Mackenzie L., Le, Nhut M, Tao, Sijia, Bryant, Joseph, Sausville, Edward, Schinazi, Raymond F, Kashuba, Angela DM, Redfield, Robert R, Heredia, Alonso
Veröffentlicht in Antivir Ther (2019)

Low-Level Ionizing Radiation Induces Selective Killing of HIV-1-Infected Cells with Reversal of Cytokine Induction Using mTOR Inhibitors

von Pinto, Daniel O., DeMarino, Catherine, Vo, Thy T., Cowen, Maria, Kim, Yuriy, Pleet, Michelle L., Barclay, Robert A., Noren Hooten, Nicole, Evans, Michele K., Heredia, Alonso, Batrakova, Elena V., Iordanskiy, Sergey, Kashanchi, Fatah
Veröffentlicht in Viruses (2020)