Low-Level Ionizing Radiation Induces Selective Killing of HIV-1-Infected Cells with Reversal of Cytokine Induction Using mTOR Inhibitors

HIV-1 infects 39.5 million people worldwide, and cART is effective in preventing viral spread by reducing HIV-1 plasma viral loads to undetectable levels. However, viral reservoirs persist by mechanisms, including the inhibition of autophagy by HIV-1 proteins (i.e., Nef and Tat). HIV-1 reservoirs ca...

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Publicado no:Viruses
Main Authors: Pinto, Daniel O., DeMarino, Catherine, Vo, Thy T., Cowen, Maria, Kim, Yuriy, Pleet, Michelle L., Barclay, Robert A., Noren Hooten, Nicole, Evans, Michele K., Heredia, Alonso, Batrakova, Elena V., Iordanskiy, Sergey, Kashanchi, Fatah
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472203/
https://ncbi.nlm.nih.gov/pubmed/32823598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12080885
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