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Extracellular Vesicle Activation of Latent HIV-1 Is Driven by EV-Associated c-Src and Cellular SRC-1 via the PI3K/AKT/mTOR Pathway

HIV-1 is a global health crisis that has infected more than 37 million people. Latent reservoirs throughout the body are a major hurdle when it comes to eradicating the virus. In our previous study, we found that exosomes, a type of extracellular vesicle (EV), from uninfected cells activate the tran...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Barclay, Robert A., Mensah, Gifty A., Cowen, Maria, DeMarino, Catherine, Kim, Yuriy, Pinto, Daniel O., Erickson, James, Kashanchi, Fatah
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354524/
https://ncbi.nlm.nih.gov/pubmed/32575590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12060665
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