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Low-Level Ionizing Radiation Induces Selective Killing of HIV-1-Infected Cells with Reversal of Cytokine Induction Using mTOR Inhibitors

HIV-1 infects 39.5 million people worldwide, and cART is effective in preventing viral spread by reducing HIV-1 plasma viral loads to undetectable levels. However, viral reservoirs persist by mechanisms, including the inhibition of autophagy by HIV-1 proteins (i.e., Nef and Tat). HIV-1 reservoirs ca...

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Bibliografiske detaljer
Udgivet i:Viruses
Main Authors: Pinto, Daniel O., DeMarino, Catherine, Vo, Thy T., Cowen, Maria, Kim, Yuriy, Pleet, Michelle L., Barclay, Robert A., Noren Hooten, Nicole, Evans, Michele K., Heredia, Alonso, Batrakova, Elena V., Iordanskiy, Sergey, Kashanchi, Fatah
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472203/
https://ncbi.nlm.nih.gov/pubmed/32823598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12080885
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