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Binding of fusion protein FLSC IgG1 to CCR5 is enhanced by CCR5 antagonist Maraviroc

The CCR5 chemokine receptor is crucial for human immunodeficiency virus type 1 (HIV-1) infection, acting as the principal coreceptor for HIV-1 entry and transmission and is thus an attractive target for antiviral therapy. Studies have suggested that CCR5 surface density and its conformational change...

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Latinovic, Olga, Schneider, Kate, Szmacinski, Henryk, Lakowicz, Joseph R., Heredia, Alonso, Redfield, Robert R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776994/
https://ncbi.nlm.nih.gov/pubmed/25453341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2014.10.006
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