IMP Dehydrogenase: Structure, Mechanism and Inhibition

av Hedstrom, Lizbeth
Publicerad 2009

The dynamic determinants of reaction specificity in the IMPDH/GMPR family of (β/α)(8) barrel enzymes

av Hedstrom, Lizbeth
Publicerad 2012

Cryptosporidium: a first step toward tractability

av Hedstrom, Lizbeth
I publikationen Trends Parasitol (2015)

The bare essentials of antibiotic target validation

av Hedstrom, Lizbeth
I publikationen ACS Infect Dis (2016)

Autosomal dominant retinitis pigmentosa mutations in inosine 5′-monophosphate dehydrogenase type I disrupt nucleic acid binding

av Mortimer, Sarah E., Hedstrom, Lizbeth
Publicerad 2005

Mushroom Tyrosinase Oxidizes Tyrosine-rich Sequences, Allowing Selective Protein Functionalization

av Long, Marcus J. C., Hedstrom, Lizbeth
Publicerad 2012

Short-lived protease–serpin complexes: Partial disruption of the rat trypsin active site

av Liu, Lu, Mushero, Nicole, Hedstrom, Lizbeth, Gershenson, Anne
Publicerad 2007

The Cys319 loop modulates the transition between dehydrogenase and hydrolase conformations in IMP dehydrogenase

av Josephine, Helen R., Ravichandran, Kanchana R., Hedstrom, Lizbeth
Publicerad 2010

Specific biotinylation of IMP dehydrogenase

av Hoefler, B. Christopher, Gollapalli, Deviprasad R., Hedstrom, Lizbeth
Publicerad 2011

Kinetically Controlled Drug Resistance: HOW PENICILLIUM BREVICOMPACTUM SURVIVES MYCOPHENOLIC ACID

av Sun, Xin E., Hansen, Bjarne Gram, Hedstrom, Lizbeth
Publicerad 2011

Inhibitor Mediated Protein Degradation

av Long, Marcus J. C., Gollapalli, Deviprasad R., Hedstrom, Lizbeth
Publicerad 2012

A structural determinant of mycophenolic acid resistance in eukaryotic inosine 5′‐monophosphate dehydrogenases

av Freedman, Rebecca, Yu, Runhan, Sarkis, Alexander W., Hedstrom, Lizbeth
I publikationen Protein Sci (2019)

A Kinetic Alignment of Orthologous Inosine-5′-monophosphate Dehydrogenases

av Riera, Thomas V., Wang, Wen, Josephine, Helen R., Hedstrom, Lizbeth
Publicerad 2008

Using supramolecular hydrogel to discover the interactions between proteins and molecular nanofibers of small molecules

av Gao, Yuan, Long, Marcus, Shi, Junfeng, Hedstrom, Lizbeth, Xu, Bing
Publicerad 2012

The antibiotic potential of prokaryotic IMP dehydrogenase inhibitors

av Hedstrom, Lizbeth, Liechti, George, Goldberg, Joanna B., Gollapalli, Deviprasad R.
I publikationen Curr Med Chem (2011)

Inhibition of IMPDH from Bacillus anthracis: Mechanism revealed by pre-steady state kinetics

av Wei, Yang, Kuzmič, Petr, Yu, Runhan, Modi, Gyan, Hedstrom, Lizbeth
I publikationen Biochemistry (2016)

Substrate and Cofactor Dynamics on Guanosine Monophosphate Reductase Probed by High Resolution Field Cycling (31)P NMR Relaxometry

av Rosenberg, Masha M., Redfield, Alfred G., Roberts, Mary F., Hedstrom, Lizbeth
I publikationen J Biol Chem (2016)

Dynamic characteristics of GMP reductase complexes revealed by high resolution (31)P field cycling NMR relaxometry

av Rosenberg, Masha M., Redfield, Alfred G., Roberts, Mary F., Hedstrom, Lizbeth
I publikationen Biochemistry (2018)

Ubiquilin-mediated Small Molecule Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling

av Coffey, Rory T., Shi, Yuntao, Long, Marcus J. C., Marr, Michael T., Hedstrom, Lizbeth
I publikationen J Biol Chem (2016)

Expression and Purification of Active Recombinant Human Alpha-1 Antitrypsin (AAT) from Escherichia coli

av Krishnan, Beena, Hedstrom, Lizbeth, Hebert, Daniel N., Gierasch, Lila M., Gershenson, Anne
I publikationen Methods Mol Biol (2017)