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The bare essentials of antibiotic target validation
The convergence of competitive fitness experiments and phenotypic screening would seem to be an auspicious beginning for validation of an antibacterial target. IMPDH was already identified an essential protein in Mycobacterium tuberculosis when not one, but two, groups discovered inhibitors with pro...
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| Publicado no: | ACS Infect Dis |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5520969/ https://ncbi.nlm.nih.gov/pubmed/28081610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00185 |
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