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Specific biotinylation of IMP dehydrogenase
IMP dehydrogenase (IMPDH) catalyzes a critical step in guanine nucleotide biosynthesis. IMPDH also has biological roles that are distinct from its enzymatic function. We report a biotin-linked reagent that selectively labels IMPDH and is released by dithiothreitol. This reagent will be invaluable in...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3044611/ https://ncbi.nlm.nih.gov/pubmed/21295473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.01.042 |
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