IMP Dehydrogenase: Structure, Mechanism and Inhibition

nork Hedstrom, Lizbeth
Argitaratua 2009

The dynamic determinants of reaction specificity in the IMPDH/GMPR family of (β/α)(8) barrel enzymes

nork Hedstrom, Lizbeth
Argitaratua 2012

Cryptosporidium: a first step toward tractability

nork Hedstrom, Lizbeth
Argitaratua izan da Trends Parasitol (2015)

The bare essentials of antibiotic target validation

nork Hedstrom, Lizbeth
Argitaratua izan da ACS Infect Dis (2016)

Autosomal dominant retinitis pigmentosa mutations in inosine 5′-monophosphate dehydrogenase type I disrupt nucleic acid binding

nork Mortimer, Sarah E., Hedstrom, Lizbeth
Argitaratua 2005

Mushroom Tyrosinase Oxidizes Tyrosine-rich Sequences, Allowing Selective Protein Functionalization

nork Long, Marcus J. C., Hedstrom, Lizbeth
Argitaratua 2012

Short-lived protease–serpin complexes: Partial disruption of the rat trypsin active site

nork Liu, Lu, Mushero, Nicole, Hedstrom, Lizbeth, Gershenson, Anne
Argitaratua 2007

The Cys319 loop modulates the transition between dehydrogenase and hydrolase conformations in IMP dehydrogenase

nork Josephine, Helen R., Ravichandran, Kanchana R., Hedstrom, Lizbeth
Argitaratua 2010

Specific biotinylation of IMP dehydrogenase

nork Hoefler, B. Christopher, Gollapalli, Deviprasad R., Hedstrom, Lizbeth
Argitaratua 2011

Kinetically Controlled Drug Resistance: HOW PENICILLIUM BREVICOMPACTUM SURVIVES MYCOPHENOLIC ACID

nork Sun, Xin E., Hansen, Bjarne Gram, Hedstrom, Lizbeth
Argitaratua 2011

Inhibitor Mediated Protein Degradation

nork Long, Marcus J. C., Gollapalli, Deviprasad R., Hedstrom, Lizbeth
Argitaratua 2012

A structural determinant of mycophenolic acid resistance in eukaryotic inosine 5′‐monophosphate dehydrogenases

nork Freedman, Rebecca, Yu, Runhan, Sarkis, Alexander W., Hedstrom, Lizbeth
Argitaratua izan da Protein Sci (2019)

A Kinetic Alignment of Orthologous Inosine-5′-monophosphate Dehydrogenases

nork Riera, Thomas V., Wang, Wen, Josephine, Helen R., Hedstrom, Lizbeth
Argitaratua 2008

Using supramolecular hydrogel to discover the interactions between proteins and molecular nanofibers of small molecules

nork Gao, Yuan, Long, Marcus, Shi, Junfeng, Hedstrom, Lizbeth, Xu, Bing
Argitaratua 2012

The antibiotic potential of prokaryotic IMP dehydrogenase inhibitors

nork Hedstrom, Lizbeth, Liechti, George, Goldberg, Joanna B., Gollapalli, Deviprasad R.
Argitaratua izan da Curr Med Chem (2011)

Inhibition of IMPDH from Bacillus anthracis: Mechanism revealed by pre-steady state kinetics

nork Wei, Yang, Kuzmič, Petr, Yu, Runhan, Modi, Gyan, Hedstrom, Lizbeth
Argitaratua izan da Biochemistry (2016)

Substrate and Cofactor Dynamics on Guanosine Monophosphate Reductase Probed by High Resolution Field Cycling (31)P NMR Relaxometry

nork Rosenberg, Masha M., Redfield, Alfred G., Roberts, Mary F., Hedstrom, Lizbeth
Argitaratua izan da J Biol Chem (2016)

Dynamic characteristics of GMP reductase complexes revealed by high resolution (31)P field cycling NMR relaxometry

nork Rosenberg, Masha M., Redfield, Alfred G., Roberts, Mary F., Hedstrom, Lizbeth
Argitaratua izan da Biochemistry (2018)

Ubiquilin-mediated Small Molecule Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling

nork Coffey, Rory T., Shi, Yuntao, Long, Marcus J. C., Marr, Michael T., Hedstrom, Lizbeth
Argitaratua izan da J Biol Chem (2016)

Expression and Purification of Active Recombinant Human Alpha-1 Antitrypsin (AAT) from Escherichia coli

nork Krishnan, Beena, Hedstrom, Lizbeth, Hebert, Daniel N., Gierasch, Lila M., Gershenson, Anne
Argitaratua izan da Methods Mol Biol (2017)