In Vitro Combination Studies of Benzothiazinone Lead Compound BTZ043 against Mycobacterium tuberculosis

od Lechartier, Benoit, Hartkoorn, Ruben C., Cole, Stewart T.
Izdano 2012

Cross-Resistance between Clofazimine and Bedaquiline through Upregulation of MmpL5 in Mycobacterium tuberculosis

od Hartkoorn, Ruben C., Uplekar, Swapna, Cole, Stewart T.
Izdano 2014

Synthesis and Antimycobacterial Activity of 2,1′-Dihydropyridomycins

od Horlacher, Oliver P., Hartkoorn, Ruben C., Cole, Stewart T., Altmann, Karl-Heinz
Izdano 2012

Genome-Wide Definition of the SigF Regulon in Mycobacterium tuberculosis

od Hartkoorn, Ruben C., Sala, Claudia, Uplekar, Swapna, Busso, Philippe, Rougemont, Jacques, Cole, Stewart T.
Izdano 2012

Streptomycin-Starved Mycobacterium tuberculosis 18b, a Drug Discovery Tool for Latent Tuberculosis

od Zhang, Ming, Sala, Claudia, Hartkoorn, Ruben C., Dhar, Neeraj, Mendoza-Losana, Alfonso, Cole, Stewart T.
Izdano 2012

Sigma Factor F Does Not Prevent Rifampin Inhibition of RNA Polymerase or Cause Rifampin Tolerance in Mycobacterium tuberculosis

od Hartkoorn, Ruben C., Sala, Claudia, Magnet, Sophie J., Chen, Jeffrey M., Pojer, Florence, Cole, Stewart T.
Izdano 2010

Mechanism of Action of 5-Nitrothiophenes against Mycobacterium tuberculosis

od Hartkoorn, Ruben C., Ryabova, Olga B., Chiarelli, Laurent R., Riccardi, Giovanna, Makarov, Vadim, Cole, Stewart T.
Izdano 2014

Bioluminescence for Assessing Drug Potency against Nonreplicating Mycobacterium tuberculosis

od Vocat, Anthony, Hartkoorn, Ruben C., Lechartier, Benoit, Zhang, Ming, Dhar, Neeraj, Cole, Stewart T., Sala, Claudia
izdano v Antimicrob Agents Chemother (2015)

Accelerated microfluidic native chemical ligation at difficult amino acids toward cyclic peptides

od Ollivier, Nathalie, Toupy, Thomas, Hartkoorn, Ruben C., Desmet, Rémi, Monbaliu, Jean-Christophe M., Melnyk, Oleg
izdano v Nat Commun (2018)

Simple Model for Testing Drugs against Nonreplicating Mycobacterium tuberculosis

od Sala, Claudia, Dhar, Neeraj, Hartkoorn, Ruben C., Zhang, Ming, Ha, Young Hwan, Schneider, Patricia, Cole, Stewart T.
Izdano 2010

Towards a new tuberculosis drug: pyridomycin – nature's isoniazid

od Hartkoorn, Ruben C, Sala, Claudia, Neres, João, Pojer, Florence, Magnet, Sophie, Mukherjee, Raju, Uplekar, Swapna, Boy-Röttger, Stefanie, Altmann, Karl-Heinz, Cole, Stewart T
Izdano 2012

A druggable secretory protein maturase of Toxoplasma essential for invasion and egress

od Dogga, Sunil Kumar, Mukherjee, Budhaditya, Jacot, Damien, Kockmann, Tobias, Molino, Luca, Hammoudi, Pierre-Mehdi, Hartkoorn, Ruben C, Hehl, Adrian B, Soldati-Favre, Dominique
izdano v eLife (2017)

The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis

od Makarov, Vadim, Neres, João, Hartkoorn, Ruben C., Ryabova, Olga B., Kazakova, Elena, Šarkan, Michal, Huszár, Stanislav, Piton, Jérémie, Kolly, Gaëlle S., Vocat, Anthony, Conroy, Trent M., Mikušová, Katarína, Cole, Stewart T.
izdano v Antimicrob Agents Chemother (2015)

HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms

od Hartkoorn, Ruben C, San Kwan, Wai, Shallcross, Victoria, Chaikan, Ammara, Liptrott, Neill, Egan, Deirdre, Enrique Salcedo Sora, J, James, Chloe E, Gibbons, Sara, Bray, Pat G, Back, David J, Khoo, Saye H, Owen, Andrew
izdano v Pharmacogenet Genomics (2010)

Characterization of new, efficient Mycobacterium tuberculosis topoisomerase-I inhibitors and their interaction with human ABC multidrug transporters

od Temesszentandrási-Ambrus, Csilla, Tóth, Szilárd, Verma, Rinkee, Bánhegyi, Péter, Szabadkai, István, Baska, Ferenc, Szántai-Kis, Csaba, Hartkoorn, Ruben C., Lingerfelt, Mary A., Sarkadi, Balázs, Szakács, Gergely, Őrfi, László, Nagaraja, Valakunja, Ekins, Sean, Telbisz, Ágnes
izdano v PLoS One (2018)

Towards a new combination therapy for tuberculosis with next generation benzothiazinones

od Makarov, Vadim, Lechartier, Benoit, Zhang, Ming, Neres, João, Sar, Astrid M, Raadsen, Susanne A, Hartkoorn, Ruben C, Ryabova, Olga B, Vocat, Anthony, Decosterd, Laurent A, Widmer, Nicolas, Buclin, Thierry, Bitter, Wilbert, Andries, Koen, Pojer, Florence, Dyson, Paul J, Cole, Stewart T
Izdano 2014

The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis

od Singh, Vinayak, Donini, Stefano, Pacitto, Angela, Sala, Claudia, Hartkoorn, Ruben C., Dhar, Neeraj, Keri, Gyorgy, Ascher, David B., Mondésert, Guillaume, Vocat, Anthony, Lupien, Andréanne, Sommer, Raphael, Vermet, Hélène, Lagrange, Sophie, Buechler, Joe, Warner, Digby F., McKinney, John D., Pato, Janos, Cole, Stewart T., Blundell, Tom L., Rizzi, Menico, Mizrahi, Valerie
izdano v ACS Infect Dis (2016)

Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG

od Mori, Giorgia, Chiarelli, Laurent R., Esposito, Marta, Makarov, Vadim, Bellinzoni, Marco, Hartkoorn, Ruben C., Degiacomi, Giulia, Boldrin, Francesca, Ekins, Sean, de Jesus Lopes Ribeiro, Ana Luisa, Marino, Leonardo B., Centárová, Ivana, Svetlíková, Zuzana, Blaško, Jaroslav, Kazakova, Elena, Lepioshkin, Alexander, Barilone, Nathalie, Zanoni, Giuseppe, Porta, Alessio, Fondi, Marco, Fani, Renato, Baulard, Alain R., Mikušová, Katarína, Alzari, Pedro M., Manganelli, Riccardo, de Carvalho, Luiz Pedro S., Riccardi, Giovanna, Cole, Stewart T., Pasca, Maria Rosalia
izdano v Chem Biol (2015)