Bioluminescence for Assessing Drug Potency against Nonreplicating Mycobacterium tuberculosis

Targeting dormant Mycobacterium tuberculosis represents a challenge to antituberculosis drug discovery programs. We previously reported and validated the use of the streptomycin (STR)-dependent M. tuberculosis 18b strain as a tool for assessing drug potency against nonreplicating bacteria both in vi...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Vocat, Anthony, Hartkoorn, Ruben C., Lechartier, Benoit, Zhang, Ming, Dhar, Neeraj, Cole, Stewart T., Sala, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468706/
https://ncbi.nlm.nih.gov/pubmed/25896710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00528-15
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