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In Vitro Combination Studies of Benzothiazinone Lead Compound BTZ043 against Mycobacterium tuberculosis

Benzothiazinones (BTZ) are a new class of drug candidates to combat tuberculosis that inhibit decaprenyl-phosphoribose epimerase (DprE1), an essential enzyme involved in arabinan biosynthesis. Using the checkerboard method and cell viability assays, we have studied the interaction profiles of BTZ043...

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Detalhes bibliográficos
Main Authors: Lechartier, Benoit, Hartkoorn, Ruben C., Cole, Stewart T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486603/
https://ncbi.nlm.nih.gov/pubmed/22926573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01476-12
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