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Genome-Wide Definition of the SigF Regulon in Mycobacterium tuberculosis

In Mycobacterium tuberculosis the alternative sigma factor SigF controls the expression of a particular subset of genes by altering RNA polymerase specificity. Here, we utilize two genome-wide approaches to identify SigF-binding sites: chromatin immunoprecipitation (ChIP-on-chip) and microarray anal...

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Bibliografske podrobnosti
Main Authors: Hartkoorn, Ruben C., Sala, Claudia, Uplekar, Swapna, Busso, Philippe, Rougemont, Jacques, Cole, Stewart T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318452/
https://ncbi.nlm.nih.gov/pubmed/22307756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.06692-11
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