In Vitro Combination Studies of Benzothiazinone Lead Compound BTZ043 against Mycobacterium tuberculosis

nork Lechartier, Benoit, Hartkoorn, Ruben C., Cole, Stewart T.
Argitaratua 2012

Cross-Resistance between Clofazimine and Bedaquiline through Upregulation of MmpL5 in Mycobacterium tuberculosis

nork Hartkoorn, Ruben C., Uplekar, Swapna, Cole, Stewart T.
Argitaratua 2014

Synthesis and Antimycobacterial Activity of 2,1′-Dihydropyridomycins

nork Horlacher, Oliver P., Hartkoorn, Ruben C., Cole, Stewart T., Altmann, Karl-Heinz
Argitaratua 2012

Genome-Wide Definition of the SigF Regulon in Mycobacterium tuberculosis

nork Hartkoorn, Ruben C., Sala, Claudia, Uplekar, Swapna, Busso, Philippe, Rougemont, Jacques, Cole, Stewart T.
Argitaratua 2012

Streptomycin-Starved Mycobacterium tuberculosis 18b, a Drug Discovery Tool for Latent Tuberculosis

nork Zhang, Ming, Sala, Claudia, Hartkoorn, Ruben C., Dhar, Neeraj, Mendoza-Losana, Alfonso, Cole, Stewart T.
Argitaratua 2012

Sigma Factor F Does Not Prevent Rifampin Inhibition of RNA Polymerase or Cause Rifampin Tolerance in Mycobacterium tuberculosis

nork Hartkoorn, Ruben C., Sala, Claudia, Magnet, Sophie J., Chen, Jeffrey M., Pojer, Florence, Cole, Stewart T.
Argitaratua 2010

Mechanism of Action of 5-Nitrothiophenes against Mycobacterium tuberculosis

nork Hartkoorn, Ruben C., Ryabova, Olga B., Chiarelli, Laurent R., Riccardi, Giovanna, Makarov, Vadim, Cole, Stewart T.
Argitaratua 2014

Bioluminescence for Assessing Drug Potency against Nonreplicating Mycobacterium tuberculosis

nork Vocat, Anthony, Hartkoorn, Ruben C., Lechartier, Benoit, Zhang, Ming, Dhar, Neeraj, Cole, Stewart T., Sala, Claudia
Argitaratua izan da Antimicrob Agents Chemother (2015)

Accelerated microfluidic native chemical ligation at difficult amino acids toward cyclic peptides

nork Ollivier, Nathalie, Toupy, Thomas, Hartkoorn, Ruben C., Desmet, Rémi, Monbaliu, Jean-Christophe M., Melnyk, Oleg
Argitaratua izan da Nat Commun (2018)

Simple Model for Testing Drugs against Nonreplicating Mycobacterium tuberculosis

nork Sala, Claudia, Dhar, Neeraj, Hartkoorn, Ruben C., Zhang, Ming, Ha, Young Hwan, Schneider, Patricia, Cole, Stewart T.
Argitaratua 2010

Towards a new tuberculosis drug: pyridomycin – nature's isoniazid

nork Hartkoorn, Ruben C, Sala, Claudia, Neres, João, Pojer, Florence, Magnet, Sophie, Mukherjee, Raju, Uplekar, Swapna, Boy-Röttger, Stefanie, Altmann, Karl-Heinz, Cole, Stewart T
Argitaratua 2012

A druggable secretory protein maturase of Toxoplasma essential for invasion and egress

nork Dogga, Sunil Kumar, Mukherjee, Budhaditya, Jacot, Damien, Kockmann, Tobias, Molino, Luca, Hammoudi, Pierre-Mehdi, Hartkoorn, Ruben C, Hehl, Adrian B, Soldati-Favre, Dominique
Argitaratua izan da eLife (2017)

The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis

nork Makarov, Vadim, Neres, João, Hartkoorn, Ruben C., Ryabova, Olga B., Kazakova, Elena, Šarkan, Michal, Huszár, Stanislav, Piton, Jérémie, Kolly, Gaëlle S., Vocat, Anthony, Conroy, Trent M., Mikušová, Katarína, Cole, Stewart T.
Argitaratua izan da Antimicrob Agents Chemother (2015)

HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms

nork Hartkoorn, Ruben C, San Kwan, Wai, Shallcross, Victoria, Chaikan, Ammara, Liptrott, Neill, Egan, Deirdre, Enrique Salcedo Sora, J, James, Chloe E, Gibbons, Sara, Bray, Pat G, Back, David J, Khoo, Saye H, Owen, Andrew
Argitaratua izan da Pharmacogenet Genomics (2010)

Characterization of new, efficient Mycobacterium tuberculosis topoisomerase-I inhibitors and their interaction with human ABC multidrug transporters

nork Temesszentandrási-Ambrus, Csilla, Tóth, Szilárd, Verma, Rinkee, Bánhegyi, Péter, Szabadkai, István, Baska, Ferenc, Szántai-Kis, Csaba, Hartkoorn, Ruben C., Lingerfelt, Mary A., Sarkadi, Balázs, Szakács, Gergely, Őrfi, László, Nagaraja, Valakunja, Ekins, Sean, Telbisz, Ágnes
Argitaratua izan da PLoS One (2018)

Towards a new combination therapy for tuberculosis with next generation benzothiazinones

nork Makarov, Vadim, Lechartier, Benoit, Zhang, Ming, Neres, João, Sar, Astrid M, Raadsen, Susanne A, Hartkoorn, Ruben C, Ryabova, Olga B, Vocat, Anthony, Decosterd, Laurent A, Widmer, Nicolas, Buclin, Thierry, Bitter, Wilbert, Andries, Koen, Pojer, Florence, Dyson, Paul J, Cole, Stewart T
Argitaratua 2014

The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis

nork Singh, Vinayak, Donini, Stefano, Pacitto, Angela, Sala, Claudia, Hartkoorn, Ruben C., Dhar, Neeraj, Keri, Gyorgy, Ascher, David B., Mondésert, Guillaume, Vocat, Anthony, Lupien, Andréanne, Sommer, Raphael, Vermet, Hélène, Lagrange, Sophie, Buechler, Joe, Warner, Digby F., McKinney, John D., Pato, Janos, Cole, Stewart T., Blundell, Tom L., Rizzi, Menico, Mizrahi, Valerie
Argitaratua izan da ACS Infect Dis (2016)

Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG

nork Mori, Giorgia, Chiarelli, Laurent R., Esposito, Marta, Makarov, Vadim, Bellinzoni, Marco, Hartkoorn, Ruben C., Degiacomi, Giulia, Boldrin, Francesca, Ekins, Sean, de Jesus Lopes Ribeiro, Ana Luisa, Marino, Leonardo B., Centárová, Ivana, Svetlíková, Zuzana, Blaško, Jaroslav, Kazakova, Elena, Lepioshkin, Alexander, Barilone, Nathalie, Zanoni, Giuseppe, Porta, Alessio, Fondi, Marco, Fani, Renato, Baulard, Alain R., Mikušová, Katarína, Alzari, Pedro M., Manganelli, Riccardo, de Carvalho, Luiz Pedro S., Riccardi, Giovanna, Cole, Stewart T., Pasca, Maria Rosalia
Argitaratua izan da Chem Biol (2015)