In Vitro Combination Studies of Benzothiazinone Lead Compound BTZ043 against Mycobacterium tuberculosis

অনুযায়ী Lechartier, Benoit, Hartkoorn, Ruben C., Cole, Stewart T.
প্রকাশিত 2012

Cross-Resistance between Clofazimine and Bedaquiline through Upregulation of MmpL5 in Mycobacterium tuberculosis

অনুযায়ী Hartkoorn, Ruben C., Uplekar, Swapna, Cole, Stewart T.
প্রকাশিত 2014

Synthesis and Antimycobacterial Activity of 2,1′-Dihydropyridomycins

অনুযায়ী Horlacher, Oliver P., Hartkoorn, Ruben C., Cole, Stewart T., Altmann, Karl-Heinz
প্রকাশিত 2012

Genome-Wide Definition of the SigF Regulon in Mycobacterium tuberculosis

অনুযায়ী Hartkoorn, Ruben C., Sala, Claudia, Uplekar, Swapna, Busso, Philippe, Rougemont, Jacques, Cole, Stewart T.
প্রকাশিত 2012

Streptomycin-Starved Mycobacterium tuberculosis 18b, a Drug Discovery Tool for Latent Tuberculosis

অনুযায়ী Zhang, Ming, Sala, Claudia, Hartkoorn, Ruben C., Dhar, Neeraj, Mendoza-Losana, Alfonso, Cole, Stewart T.
প্রকাশিত 2012

Sigma Factor F Does Not Prevent Rifampin Inhibition of RNA Polymerase or Cause Rifampin Tolerance in Mycobacterium tuberculosis

অনুযায়ী Hartkoorn, Ruben C., Sala, Claudia, Magnet, Sophie J., Chen, Jeffrey M., Pojer, Florence, Cole, Stewart T.
প্রকাশিত 2010

Mechanism of Action of 5-Nitrothiophenes against Mycobacterium tuberculosis

অনুযায়ী Hartkoorn, Ruben C., Ryabova, Olga B., Chiarelli, Laurent R., Riccardi, Giovanna, Makarov, Vadim, Cole, Stewart T.
প্রকাশিত 2014

Bioluminescence for Assessing Drug Potency against Nonreplicating Mycobacterium tuberculosis

অনুযায়ী Vocat, Anthony, Hartkoorn, Ruben C., Lechartier, Benoit, Zhang, Ming, Dhar, Neeraj, Cole, Stewart T., Sala, Claudia
প্রকাশিত Antimicrob Agents Chemother (2015)

Accelerated microfluidic native chemical ligation at difficult amino acids toward cyclic peptides

অনুযায়ী Ollivier, Nathalie, Toupy, Thomas, Hartkoorn, Ruben C., Desmet, Rémi, Monbaliu, Jean-Christophe M., Melnyk, Oleg
প্রকাশিত Nat Commun (2018)

Simple Model for Testing Drugs against Nonreplicating Mycobacterium tuberculosis

অনুযায়ী Sala, Claudia, Dhar, Neeraj, Hartkoorn, Ruben C., Zhang, Ming, Ha, Young Hwan, Schneider, Patricia, Cole, Stewart T.
প্রকাশিত 2010

Towards a new tuberculosis drug: pyridomycin – nature's isoniazid

অনুযায়ী Hartkoorn, Ruben C, Sala, Claudia, Neres, João, Pojer, Florence, Magnet, Sophie, Mukherjee, Raju, Uplekar, Swapna, Boy-Röttger, Stefanie, Altmann, Karl-Heinz, Cole, Stewart T
প্রকাশিত 2012

A druggable secretory protein maturase of Toxoplasma essential for invasion and egress

অনুযায়ী Dogga, Sunil Kumar, Mukherjee, Budhaditya, Jacot, Damien, Kockmann, Tobias, Molino, Luca, Hammoudi, Pierre-Mehdi, Hartkoorn, Ruben C, Hehl, Adrian B, Soldati-Favre, Dominique
প্রকাশিত eLife (2017)

The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis

অনুযায়ী Makarov, Vadim, Neres, João, Hartkoorn, Ruben C., Ryabova, Olga B., Kazakova, Elena, Šarkan, Michal, Huszár, Stanislav, Piton, Jérémie, Kolly, Gaëlle S., Vocat, Anthony, Conroy, Trent M., Mikušová, Katarína, Cole, Stewart T.
প্রকাশিত Antimicrob Agents Chemother (2015)

HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms

অনুযায়ী Hartkoorn, Ruben C, San Kwan, Wai, Shallcross, Victoria, Chaikan, Ammara, Liptrott, Neill, Egan, Deirdre, Enrique Salcedo Sora, J, James, Chloe E, Gibbons, Sara, Bray, Pat G, Back, David J, Khoo, Saye H, Owen, Andrew
প্রকাশিত Pharmacogenet Genomics (2010)

Characterization of new, efficient Mycobacterium tuberculosis topoisomerase-I inhibitors and their interaction with human ABC multidrug transporters

অনুযায়ী Temesszentandrási-Ambrus, Csilla, Tóth, Szilárd, Verma, Rinkee, Bánhegyi, Péter, Szabadkai, István, Baska, Ferenc, Szántai-Kis, Csaba, Hartkoorn, Ruben C., Lingerfelt, Mary A., Sarkadi, Balázs, Szakács, Gergely, Őrfi, László, Nagaraja, Valakunja, Ekins, Sean, Telbisz, Ágnes
প্রকাশিত PLoS One (2018)

Towards a new combination therapy for tuberculosis with next generation benzothiazinones

অনুযায়ী Makarov, Vadim, Lechartier, Benoit, Zhang, Ming, Neres, João, Sar, Astrid M, Raadsen, Susanne A, Hartkoorn, Ruben C, Ryabova, Olga B, Vocat, Anthony, Decosterd, Laurent A, Widmer, Nicolas, Buclin, Thierry, Bitter, Wilbert, Andries, Koen, Pojer, Florence, Dyson, Paul J, Cole, Stewart T
প্রকাশিত 2014

The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis

অনুযায়ী Singh, Vinayak, Donini, Stefano, Pacitto, Angela, Sala, Claudia, Hartkoorn, Ruben C., Dhar, Neeraj, Keri, Gyorgy, Ascher, David B., Mondésert, Guillaume, Vocat, Anthony, Lupien, Andréanne, Sommer, Raphael, Vermet, Hélène, Lagrange, Sophie, Buechler, Joe, Warner, Digby F., McKinney, John D., Pato, Janos, Cole, Stewart T., Blundell, Tom L., Rizzi, Menico, Mizrahi, Valerie
প্রকাশিত ACS Infect Dis (2016)

Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG

অনুযায়ী Mori, Giorgia, Chiarelli, Laurent R., Esposito, Marta, Makarov, Vadim, Bellinzoni, Marco, Hartkoorn, Ruben C., Degiacomi, Giulia, Boldrin, Francesca, Ekins, Sean, de Jesus Lopes Ribeiro, Ana Luisa, Marino, Leonardo B., Centárová, Ivana, Svetlíková, Zuzana, Blaško, Jaroslav, Kazakova, Elena, Lepioshkin, Alexander, Barilone, Nathalie, Zanoni, Giuseppe, Porta, Alessio, Fondi, Marco, Fani, Renato, Baulard, Alain R., Mikušová, Katarína, Alzari, Pedro M., Manganelli, Riccardo, de Carvalho, Luiz Pedro S., Riccardi, Giovanna, Cole, Stewart T., Pasca, Maria Rosalia
প্রকাশিত Chem Biol (2015)