Generation and Characterization of the Anp32e-Deficient Mouse

by Reilly, Patrick T., Afzal, Samia, Wakeham, Andrew, Haight, Jillian, You-Ten, Annick, Zaugg, Kathrin, Dembowy, Joanna, Young, Ashley, Mak, Tak W.
Published 2010

E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling

by Dominguez-Brauer, Carmen, Khatun, Rahima, Elia, Andrew J., Thu, Kelsie L., Ramachandran, Parameswaran, Baniasadi, Shakiba P., Hao, Zhenyue, Jones, Lisa D., Haight, Jillian, Sheng, Yi, Mak, Tak W.
Published in Proc Natl Acad Sci U S A (2017)

Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

by Kamizono, Shintaro, Duncan, Gordon S., Seidel, Markus G., Morimoto, Akira, Hamada, Koichi, Grosveld, Gerard, Akashi, Koichi, Lind, Evan F., Haight, Jillian P., Ohashi, Pamela S., Look, A. Thomas, Mak, Tak W.
Published 2009

Acidic nuclear phosphoprotein 32kDa (ANP32)B-deficient mouse reveals a hierarchy of ANP32 importance in mammalian development

by Reilly, Patrick T., Afzal, Samia, Gorrini, Chiara, Lui, Koren, Bukhman, Yury V., Wakeham, Andrew, Haight, Jillian, Ling, Teo Wei, Cheung, Carol C., Elia, Andrew J., Turner, Patricia V., Mak, Tak Wah
Published 2011

Concerted roles of PTEN and ATM in controlling hematopoietic stem cell fitness and dormancy

by Fortin, Jerome, Bassi, Christian, Ramachandran, Parameswaran, Li, Wanda Y., Tian, Ruxiao, Zarrabi, Ida, Hill, Graham, Snow, Bryan E., Haight, Jillian, Tobin, Chantal, Hodgson, Kelsey, Wakeham, Andrew, Stambolic, Vuk, Mak, Tak W.
Published in J Clin Invest (2021)

Fas Receptor Expression in Germinal-Center B Cells Is Essential for T and B Lymphocyte Homeostasis

by Hao, Zhenyue, Duncan, Gordon S., Seagal, Jane, Su, Yu-Wen, Hong, Claire, Haight, Jillian, Chen, Nien-Jung, Elia, Andrew, Wakeham, Andrew, Li, Wanda Y., Liepa, Jennifer, Wood, Geoffrey A., Casola, Stefano, Rajewsky, Klaus, Mak, Tak W.
Published 2008

Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis

by Afzal, Samia, Hao, Zhenyue, Itsumi, Momoe, Abouelkheer, Yasser, Brenner, Dirk, Gao, Yunfei, Wakeham, Andrew, Hong, Claire, Li, Wanda Y., Sylvester, Jennifer, Gilani, Syed O., Brüstle, Anne, Haight, Jillian, You-Ten, Annick J., Lin, Gloria H. Y., Inoue, Satoshi, Mak, Tak W.
Published in Proc Natl Acad Sci U S A (2015)

DIPG-13. A NOVEL MOUSE MODEL REVEALS UNEXPECTED MECHANISMS OF ACTION OF ACVR1 MUTATIONS IN DIFFUSE INTRINSIC PONTINE GLIOMA

by Fortin, Jerome, Tian, Ruxiao, Zarrabi, Ida, Hill, Graham, Williams, Eleanor, Sanchez-Duffhues, Gonzalo, Thorikay, Midory, Ramachandran, Parameswaran, Siddaway, Robert, Wong, Jong, Haight, Jillian, You-Ten, Annick, Snow, Bryan, Wakeham, Andrew, Schramek, Daniel, Bullock, Alex, Dijke, Peter ten, Hawkins, Cynthia, Mak, Tak
Published in Neuro Oncol (2019)

Fcmr regulates mononuclear phagocyte control of anti-tumor immunity

by Kubli, Shawn P., Vornholz, Larsen, Duncan, Gordon, Zhou, Wenjing, Ramachandran, Parameswaran, Fortin, Jerome, Cox, Maureen, Han, SeongJun, Nechanitzky, Robert, Nechanitzky, Duygu, Snow, Bryan E., Jones, Lisa, Li, Wanda Y., Haight, Jillian, Wakeham, Andrew, Bray, Mark R., Mak, Tak W.
Published in Nat Commun (2019)

Author Correction: Fcmr regulates mononuclear phagocyte control of anti-tumor immunity

by Kubli, Shawn P., Vornholz, Larsen, Duncan, Gordon, Zhou, Wenjing, Ramachandran, Parameswaran, Fortin, Jerome, Cox, Maureen, Han, SeongJun, Nechanitzky, Robert, Nechanitzky, Duygu, Snow, Bryan E., Jones, Lisa, Li, Wanda Y., Haight, Jillian, Wakeham, Andrew, Bray, Mark R., Mak, Tak W.
Published in Nat Commun (2019)

TAp73 is required for spermatogenesis and the maintenance of male fertility

by Inoue, Satoshi, Tomasini, Richard, Rufini, Alessandro, Elia, Andrew J., Agostini, Massimiliano, Amelio, Ivano, Cescon, Dave, Dinsdale, David, Zhou, Lily, Harris, Isaac S., Lac, Sophie, Silvester, Jennifer, Li, Wanda Y., Sasaki, Masato, Haight, Jillian, Brüstle, Anne, Wakeham, Andrew, Mckerlie, Colin, Jurisicova, Andrea, Melino, Gerry, Mak, Tak W.
Published 2014

D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function

by Sasaki, Masato, Knobbe, Christiane B., Itsumi, Momoe, Elia, Andrew J., Harris, Isaac S., Chio, Iok In Christine, Cairns, Rob A., McCracken, Susan, Wakeham, Andrew, Haight, Jillian, Ten, Annick You, Snow, Bryan, Ueda, Takeshi, Inoue, Satoshi, Yamamoto, Kazuo, Ko, Myunggon, Rao, Anjana, Yen, Katharine E., Su, Shinsan M., Mak, Tak Wah
Published 2012

K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression

by Hao, Zhenyue, Sheng, Yi, Duncan, Gordon S., Li, Wanda Y., Dominguez, Carmen, Sylvester, Jennifer, Su, Yu-Wen, Lin, Gloria H.Y., Snow, Bryan E., Brenner, Dirk, You-Ten, Annick, Haight, Jillian, Inoue, Satoshi, Wakeham, Andrew, Elford, Alisha, Hamilton, Sara, Liang, Yi, Zúñiga-Pflücker, Juan C., He, Housheng Hansen, Ohashi, Pamela S., Mak, Tak W.
Published in Nat Commun (2017)

Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas

by Fortin, Jerome, Tian, Ruxiao, Zarrabi, Ida, Hill, Graham, Williams, Eleanor, Sanchez-Duffhues, Gonzalo, Thorikay, Midory, Ramachandran, Parameswaran, Siddaway, Robert, Wong, Jong Fu, Wu, Annette, Apuzzo, Lorraine N., Haight, Jillian, You-Ten, Annick, Snow, Bryan E., Wakeham, Andrew, Goldhamer, David J., Schramek, Daniel, Bullock, Alex N., Dijke, Peter ten, Hawkins, Cynthia, Mak, Tak W.
Published in Cancer Cell (2020)

Choline acetyltransferase-expressing T cells are required to control chronic viral infection

by Cox, Maureen A., Duncan, Gordon S., Lin, Gloria H. Y., Steinberg, Benjamin E., Yu, Lisa X., Brenner, Dirk, Buckler, Luke N., Elia, Andrew J., Wakeham, Andrew C., Nieman, Brian, Dominguez-Brauer, Carmen, Elford, Alisha R., Gill, Kyle T., Kubli, Shawn P., Haight, Jillian, Berger, Thorsten, Ohashi, Pamela S., Tracey, Kevin J., Olofsson, Peder S., Mak, Tak W.
Published in Science (2019)

IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics

by Sasaki, Masato, Knobbe, Christiane B., Munger, Joshua C., Lind, Evan F., Brenner, Dirk, Brüstle, Anne, Harris, Isaac S., Holmes, Roxanne, Wakeham, Andrew, Haight, Jillian, You-Ten, Annick, Li, Wanda Y., Schalm, Stefanie, Su, Shinsan M., Virtanen, Carl, Reifenberger, Guido, Ohashi, Pamela S., Barber, Dwayne L., Figueroa, Maria E., Melnick, Ari, Zúñiga-Pflücker, Juan-Carlos, Mak, Tak W.
Published 2012

The E3 ubiquitin ligase Mule acts through the ATM–p53 axis to maintain B lymphocyte homeostasis

by Hao, Zhenyue, Duncan, Gordon S., Su, Yu-Wen, Li, Wanda Y., Silvester, Jennifer, Hong, Claire, You, Han, Brenner, Dirk, Gorrini, Chiara, Haight, Jillian, Wakeham, Andrew, You-Ten, Annick, McCracken, Susan, Elia, Andrew, Li, Qinxi, Detmar, Jacqui, Jurisicova, Andrea, Hobeika, Elias, Reth, Michael, Sheng, Yi, Lang, Philipp A., Ohashi, Pamela S., Zhong, Qing, Wang, Xiaodong, Mak, Tak W.
Published 2012

Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15

by Inoue, Satoshi, Hao, Zhenyue, Elia, Andrew J., Cescon, David, Zhou, Lily, Silvester, Jennifer, Snow, Bryan, Harris, Isaac S., Sasaki, Masato, Li, Wanda Y., Itsumi, Momoe, Yamamoto, Kazuo, Ueda, Takeshi, Dominguez-Brauer, Carmen, Gorrini, Chiara, Chio, Iok In Christine, Haight, Jillian, You-Ten, Annick, McCracken, Susan, Wakeham, Andrew, Ghazarian, Danny, Penn, Linda J.Z., Melino, Gerry, Mak, Tak W.
Published 2013

Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation

by Dominguez-Brauer, Carmen, Hao, Zhenyue, Elia, Andrew J., Fortin, Jérôme M., Nechanitzky, Robert, Brauer, Patrick M., Sheng, Yi, Mana, Miyeko D., Chio, Iok In Christine, Haight, Jillian, Pollett, Aaron, Cairns, Robert, Tworzyanski, Leanne, Inoue, Satoshi, Reardon, Colin, Marques, Ana, Silvester, Jennifer, Cox, Maureen A., Wakeham, Andrew, Yilmaz, Omer H., Sabatini, David M., van Es, Johan H., Clevers, Hans, Sato, Toshiro, Mak, Tak W.
Published in Cell Stem Cell (2016)

Involvement of Toso in activation of monocytes, macrophages, and granulocytes

by Lang, Karl S., Lang, Philipp A., Meryk, Andreas, Pandyra, Aleksandra A., Boucher, Louis-Martin, Pozdeev, Vitaly I., Tusche, Michael W., Göthert, Joachim R., Haight, Jillian, Wakeham, Andrew, You-Ten, Annick J., McIlwain, David R., Merches, Katja, Khairnar, Vishal, Recher, Mike, Nolan, Garry P., Hitoshi, Yasumichi, Funkner, Pauline, Navarini, Alexander A., Verschoor, Admar, Shaabani, Namir, Honke, Nadine, Penn, Linda Z., Ohashi, Pamela S., Häussinger, Dieter, Lee, Kyeong-Hee, Mak, Tak W.
Published 2013