PPARα blocks glucocorticoid receptor α-mediated transactivation but cooperates with the activated glucocorticoid receptor α for transrepression on NF-κB

অনুযায়ী Bougarne, Nadia, Paumelle, Réjane, Caron, Sandrine, Hennuyer, Nathalie, Mansouri, Roxane, Gervois, Philippe, Staels, Bart, Haegeman, Guy, De Bosscher, Karolien
প্রকাশিত 2009

A fully dissociated compound of plant origin for inflammatory gene repression

অনুযায়ী De Bosscher, Karolien, Berghe, Wim Vanden, Beck, Ilse M. E., Van Molle, Wim, Hennuyer, Nathalie, Hapgood, Janet, Libert, Claude, Staels, Bart, Louw, Ann, Haegeman, Guy
প্রকাশিত 2005

Effect of 6-Benzoyl-benzothiazol-2-one scaffold on the pharmacological profile of α-alkoxyphenylpropionic acid derived PPAR agonists

অনুযায়ী Hurtevent, Aurélie, Le Naour, Morgan, Leclerc, Veronique, Carato, Pascal, Melnyk, Patricia, Hennuyer, Nathalie, Staels, Bart, Beucher-Gaudin, Monique, Caignard, Daniel-Henri, Dacquet, Catherine, Lebegue, Nicolas
প্রকাশিত J Enzyme Inhib Med Chem (2020)

Proteasomal degradation of retinoid X receptor α reprograms transcriptional activity of PPARγ in obese mice and humans

অনুযায়ী Lefebvre, Bruno, Benomar, Yacir, Guédin, Aurore, Langlois, Audrey, Hennuyer, Nathalie, Dumont, Julie, Bouchaert, Emmanuel, Dacquet, Catherine, Pénicaud, Luc, Casteilla, Louis, Pattou, Francois, Ktorza, Alain, Staels, Bart, Lefebvre, Philippe
প্রকাশিত 2010

The Nuclear Orphan Receptor Nur77 Is a Lipotoxicity Sensor Regulating Glucose-Induced Insulin Secretion in Pancreatic β-Cells

অনুযায়ী Briand, Olivier, Helleboid-Chapman, Audrey, Ploton, Maheul, Hennuyer, Nathalie, Carpentier, Rodolphe, Pattou, François, Vandewalle, Brigitte, Moerman, Ericka, Gmyr, Valery, Kerr-Conte, Julie, Eeckhoute, Jérôme, Staels, Bart, Lefebvre, Philippe
প্রকাশিত Mol Endocrinol (2012)

Increased ABCA1 activity protects against atherosclerosis

অনুযায়ী Singaraja, Roshni R., Fievet, Catherine, Castro, Graciela, James, Erick R., Hennuyer, Nathalie, Clee, Susanne M., Bissada, Nagat, Choy, Jonathan C., Fruchart, Jean-Charles, McManus, Bruce M., Staels, Bart, Hayden, Michael R.
প্রকাশিত 2002

Chromatin recruitment of activated AMPK drives fasting response genes co-controlled by GR and PPARα

অনুযায়ী Ratman, Dariusz, Mylka, Viacheslav, Bougarne, Nadia, Pawlak, Michal, Caron, Sandrine, Hennuyer, Nathalie, Paumelle, Réjane, De Cauwer, Lode, Thommis, Jonathan, Rider, Mark H., Libert, Claude, Lievens, Sam, Tavernier, Jan, Staels, Bart, De Bosscher, Karolien
প্রকাশিত Nucleic Acids Res (2016)

Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-β hydrolysis

অনুযায়ী Charton, Julie, Gauriot, Marion, Guo, Qing, Hennuyer, Nathalie, Marechal, Xavier, Dumont, Julie, Hamdane, Malika, Pottiez, Virginie, Landry, Valerie, Sperandio, Olivier, Flipo, Marion, Buee, Luc, Staels, Bart, Leroux, Florence, Tang, Wei-Jen, Deprez, Benoit, Deprez-Poulain, Rebecca
প্রকাশিত 2014

The logic of transcriptional regulator recruitment architecture at cis-regulatory modules controlling liver functions

অনুযায়ী Dubois-Chevalier, Julie, Dubois, Vanessa, Dehondt, Hélène, Mazrooei, Parisa, Mazuy, Claire, Sérandour, Aurélien A., Gheeraert, Céline, Guillaume, Penderia, Baugé, Eric, Derudas, Bruno, Hennuyer, Nathalie, Paumelle, Réjane, Marot, Guillemette, Carroll, Jason S., Lupien, Mathieu, Staels, Bart, Lefebvre, Philippe, Eeckhoute, Jérôme
প্রকাশিত Genome Res (2017)

Structure-activity relationships of Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human Insulin-Degrading Enzyme

অনুযায়ী Charton, Julie, Gauriot, Marion, Totobenazara, Jane, Hennuyer, Nathalie, Dumont, Julie, Bosc, Damien, Marechal, Xavier, Elbakali, Jamal, Herledan, Adrien, Wen, Xiaoan, Ronco, Cyril, Gras-Masse, Helene, Heninot, Antoine, Pottiez, Virginie, Landry, Valerie, Staels, Bart, Liang, Wenguang G., Leroux, Florence, Tang, Wei-Jen, Deprez, Benoit, Deprez-Poulain, Rebecca
প্রকাশিত Eur J Med Chem (2014)

CDKN2A/p16INK4a suppresses hepatic fatty acid oxidation through the AMPKα2-SIRT1-PPARα signaling pathway

অনুযায়ী Deleye, Yann, Cotte, Alexia Karen, Hannou, Sarah Anissa, Hennuyer, Nathalie, Bernard, Lucie, Derudas, Bruno, Caron, Sandrine, Legry, Vanessa, Vallez, Emmanuelle, Dorchies, Emilie, Martin, Nathalie, Lancel, Steve, Annicotte, Jean Sébastien, Bantubungi, Kadiombo, Pourtier, Albin, Raverdy, Violeta, Pattou, François, Lefebvre, Philippe, Abbadie, Corinne, Staels, Bart, Haas, Joel T., Paumelle, Réjane
প্রকাশিত J Biol Chem (2020)

Interspecies NASH disease activity whole-genome profiling identifies a fibrogenic role of PPARα-regulated dermatopontin

অনুযায়ী Lefebvre, Philippe, Lalloyer, Fanny, Baugé, Eric, Pawlak, Michal, Gheeraert, Céline, Dehondt, Hélène, Vanhoutte, Jonathan, Woitrain, Eloise, Hennuyer, Nathalie, Mazuy, Claire, Bobowski-Gérard, Marie, Zummo, Francesco Paolo, Derudas, Bruno, Driessen, Ann, Hubens, Guy, Vonghia, Luisa, Kwanten, Wilhelmus J., Michielsen, Peter, Vanwolleghem, Thomas, Eeckhoute, Jérôme, Verrijken, An, Van Gaal, Luc, Francque, Sven, Staels, Bart
প্রকাশিত JCI Insight (2017)

Hepatic PPARα is critical in the metabolic adaptation to sepsis

অনুযায়ী Paumelle, Réjane, Haas, Joel, Hennuyer, Nathalie, Bauge, Eric, Deleye, Yann, Mesotten, Dieter, Langouche, Lies, Vanhoutte, Jonathan, Cudejko, Céline, Wouters, Kristiaan, Hannou, Sarah Anissa, Legry, Vanessa, Lancel, Steve, Lalloyer, Fanny, Polizzi, Arnaud, Smati, Sarra, Gourdy, Pierre, Vallez, Emmanuelle, Bouchaert, Emmanuel, Derudas, Bruno, Dehondt, Hélène, Gheeraert, Céline, Fleury, Sébastien, Tailleux, Anne, Montagner, Alexandra, Wahli, Walter, Van Den Berghe, Greet, Guillou, Hervé, Dombrowicz, David, Staels, Bart
প্রকাশিত J Hepatol (2019)

Farnesoid X Receptor Inhibits Glucagon-Like Peptide-1 Production by Enteroendocrine L-cells

অনুযায়ী TRABELSI, Mohamed-Sami, DAOUDI, Mehdi, PRAWITT, Janne, DUCASTEL, Sarah, TOUCHE, Véronique, SAYIN, Sama I., PERINO, Alessia, BRIGHTON, Cheryl A., SEBTI, Yasmine, KLUZA, Jérôme, BRIAND, Olivier, DEHONDT, Hélène, VALLEZ, Emmanuelle, DORCHIES, Emilie, BAUD, Grégory, SPINELLI, Valeria, HENNUYER, Nathalie, CARON, Sandrine, BANTUBUNGI, Kadiombo, CAIAZZO, Robert, REIMANN, Frank, MARCHETTI, Philippe, LEFEBVRE, Philippe, BÄCKHED, Fredrik, GRIBBLE, Fiona M., SCHOONJANS, Kristina, PATTOU, François, TAILLEUX, Anne, STAELS, Bart, LESTAVEL, Sophie
প্রকাশিত Nat Commun (2015)

Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice

অনুযায়ী Deprez-Poulain, Rebecca, Hennuyer, Nathalie, Bosc, Damien, Liang, Wenguang G., Enée, Emmanuelle, Marechal, Xavier, Charton, Julie, Totobenazara, Jane, Berte, Gonzague, Jahklal, Jouda, Verdelet, Tristan, Dumont, Julie, Dassonneville, Sandrine, Woitrain, Eloise, Gauriot, Marion, Paquet, Charlotte, Duplan, Isabelle, Hermant, Paul, Cantrelle, François- Xavier, Sevin, Emmanuel, Culot, Maxime, Landry, Valerie, Herledan, Adrien, Piveteau, Catherine, Lippens, Guy, Leroux, Florence, Tang, Wei-Jen, van Endert, Peter, Staels, Bart, Deprez, Benoit
প্রকাশিত Nat Commun (2015)