Elucidating Tau function and dysfunction in the era of cryo-EM

por Lippens, Guy, Gigant, Benoît
Publicado en J Biol Chem (2019)

Post-translational modification: nature’s escape from genetic imprisonment and the basis for dynamic information encoding

por Prabakaran, Sudhakaran, Lippens, Guy, Steen, Hanno, Gunawardena, Jeremy
Publicado 2012

Phosphorylation in intrinsically disordered regions regulates the activity of Neurogenin2

por McDowell, Gary S, Hindley, Christopher J, Lippens, Guy, Landrieu, Isabelle, Philpott, Anna
Publicado en BMC Biochem (2014)

Ranking High Affinity Ligands of Low Solubility by NMR Spectroscopy

por Landrieu, Isabelle, Hanoulle, Xavier, Fritzinger, Bernd, Horvath, Dragos, Wieruszeski, Jean-Michel, Lippens, Guy
Publicado 2011

The molecular basis for an ancient partnership between Prolyl Isomerase Pin1 and Phosphatase Inhibitor-2

por Sami, Furqan, Smet-Nocca, Caroline, Khan, Meera, Landrieu, Isabelle, Lippens, Guy, Brautigan, David L.
Publicado 2011

Efficient in vivo synthesis of lasso peptide pseudomycoidin proceeds in the absence of both the leader and the leader peptidase

por Zyubko, Tatyana, Serebryakova, Marina, Andreeva, Julia, Metelev, Mikhail, Lippens, Guy, Dubiley, Svetlana, Severinov, Konstantin
Publicado en Chem Sci (2019)

Spectroscopic Studies of GSK3β Phosphorylation of the Neuronal Tau Protein and Its Interaction with the N-terminal Domain of Apolipoprotein E

por Leroy, Arnaud, Landrieu, Isabelle, Huvent, Isabelle, Legrand, Dominique, Codeville, Bernadette, Wieruszeski, Jean-Michel, Lippens, Guy
Publicado 2010

Hepatitis C Virus NS5B and Host Cyclophilin A Share a Common Binding Site on NS5A

por Rosnoblet, Claire, Fritzinger, Bernd, Legrand, Dominique, Launay, Hélène, Wieruszeski, Jean-Michel, Lippens, Guy, Hanoulle, Xavier
Publicado 2012

Characterization of Neuronal Tau Protein as a Target of Extracellular Signal-regulated Kinase

por Qi, Haoling, Prabakaran, Sudhakaran, Cantrelle, François-Xavier, Chambraud, Béatrice, Gunawardena, Jeremy, Lippens, Guy, Landrieu, Isabelle
Publicado en J Biol Chem (2016)

Comparative analysis of Erk phosphorylation suggests a mixed strategy for measuring phospho-form distributions

por Prabakaran, Sudhakaran, Everley, Robert A, Landrieu, Isabelle, Wieruszeski, Jean-Michel, Lippens, Guy, Steen, Hanno, Gunawardena, Jeremy
Publicado 2011

Hepatitis C Virus NS5A Protein Is a Substrate for the Peptidyl-prolyl cis/trans Isomerase Activity of Cyclophilins A and B

por Hanoulle, Xavier, Badillo, Aurélie, Wieruszeski, Jean-Michel, Verdegem, Dries, Landrieu, Isabelle, Bartenschlager, Ralf, Penin, François, Lippens, Guy
Publicado 2009

The Zebra Mussel (Dreissena polymorpha) as a Model Organism for Ecotoxicological Studies: A Prior (1)H NMR Spectrum Interpretation of a Whole Body Extract for Metabolism Monitoring

por Prud’homme, Sophie Martine, Hani, Younes Mohamed Ismail, Cox, Neil, Lippens, Guy, Nuzillard, Jean-Marc, Geffard, Alain
Publicado en Metabolites (2020)

NMR Meets Tau: Insights into Its Function and Pathology

por Lippens, Guy, Landrieu, Isabelle, Smet, Caroline, Huvent, Isabelle, Gandhi, Neha S., Gigant, Benoît, Despres, Clément, Qi, Haoling, Lopez, Juan
Publicado en Biomolecules (2016)

NMR reveals the intrinsically disordered domain 2 of NS5A protein as an allosteric regulator of the hepatitis C virus RNA polymerase NS5B

por Bessa, Luiza M., Launay, Hélène, Dujardin, Marie, Cantrelle, François-Xavier, Lippens, Guy, Landrieu, Isabelle, Schneider, Robert, Hanoulle, Xavier
Publicado en J Biol Chem (2017)

Tau Aggregation in Alzheimer's Disease: What Role for Phosphorylation?

por Lippens, Guy, Sillen, Alain, Landrieu, Isabelle, Amniai, Laziza, Sibille, Nathalie, Barbier, Pascale, Leroy, Arnaud, Hanoulle, Xavier, Wieruszeski, Jean-Michel
Publicado 2007

Domain 3 of NS5A Protein from the Hepatitis C Virus Has Intrinsic α-Helical Propensity and Is a Substrate of Cyclophilin A

por Verdegem, Dries, Badillo, Aurélie, Wieruszeski, Jean-Michel, Landrieu, Isabelle, Leroy, Arnaud, Bartenschlager, Ralf, Penin, François, Lippens, Guy, Hanoulle, Xavier
Publicado 2011

Molecular Implication of PP2A and Pin1 in the Alzheimer's Disease Specific Hyperphosphorylation of Tau

por Landrieu, Isabelle, Smet-Nocca, Caroline, Amniai, Laziza, Louis, Justin Vijay, Wieruszeski, Jean-Michel, Goris, Jozef, Janssens, Veerle, Lippens, Guy
Publicado 2011

Systematic Identification of Tubulin-interacting Fragments of the Microtubule-associated Protein Tau Leads to a Highly Efficient Promoter of Microtubule Assembly

por Fauquant, Caroline, Redeker, Virginie, Landrieu, Isabelle, Wieruszeski, Jean-Michel, Verdegem, Dries, Laprévote, Olivier, Lippens, Guy, Gigant, Benoît, Knossow, Marcel
Publicado 2011

The Talin Rod IBS2 α-Helix Interacts with the β3 Integrin Cytoplasmic Tail Membrane-proximal Helix by Establishing Charge Complementary Salt Bridges

por Rodius, Sophie, Chaloin, Olivier, Moes, Michèle, Schaffner-Reckinger, Elisabeth, Landrieu, Isabelle, Lippens, Guy, Lin, Minghui, Zhang, Ji, Kieffer, Nelly
Publicado 2008

Cyclophilin A allows the allosteric regulation of a structural motif in the disordered domain 2 of NS5A and thereby fine-tunes HCV RNA replication

por Dujardin, Marie, Madan, Vanesa, Gandhi, Neha S., Cantrelle, François-Xavier, Launay, Hélène, Huvent, Isabelle, Bartenschlager, Ralf, Lippens, Guy, Hanoulle, Xavier
Publicado en J Biol Chem (2019)