In vivo pieces of the PP2A onco-puzzle fallen into place

Por Meeusen, Bob, Janssens, Veerle
Publicado no Oncoscience (2017)

Targeted Therapies in Type II Endometrial Cancers: Too Little, but Not Too Late

Por Remmerie, Michiel, Janssens, Veerle
Publicado no Int J Mol Sci (2018)

PP2A: A Promising Biomarker and Therapeutic Target in Endometrial Cancer

Por Remmerie, Michiel, Janssens, Veerle
Publicado no Front Oncol (2019)

Diversity in genomic organisation, developmental regulation and distribution of the murine PR72/B" subunits of protein phosphatase 2A

Por Zwaenepoel, Karen, Louis, Justin V, Goris, Jozef, Janssens, Veerle
Publicado em 2008

The Basic Biology of PP2A in Hematologic Cells and Malignancies

Por Haesen, Dorien, Sents, Ward, Lemaire, Katleen, Hoorne, Yana, Janssens, Veerle
Publicado no Front Oncol (2014)

Protein kinase D displays intrinsic Tyr autophosphorylation activity: insights into mechanism and regulation

Por Cobbaut, Mathias, Derua, Rita, Parker, Peter J., Waelkens, Etienne, Janssens, Veerle, Van Lint, Johan
Publicado no FEBS Lett (2018)

Specific interactions of PP2A and PP2A-like phosphatases with the yeast PTPA homologues, Ypa1 and Ypa2

Por Van Hoof, Christine, Martens, Ellen, Longin, Sari, Jordens, Jan, Stevens, Ilse, Janssens, Veerle, Goris, Jozef
Publicado em 2005

PP2A binds to the LIM domains of lipoma-preferred partner through its PR130/B″ subunit to regulate cell adhesion and migration

Por Janssens, Veerle, Zwaenepoel, Karen, Rossé, Carine, Petit, Marleen M. R., Goris, Jozef, Parker, Peter J.
Publicado no J Cell Sci (2016)

Glucose-induced posttranslational activation of protein phosphatases PP2A and PP1 in yeast

Por Castermans, Dries, Somers, Ils, Kriel, Johan, Louwet, Wendy, Wera, Stefaan, Versele, Matthias, Janssens, Veerle, Thevelein, Johan M
Publicado em 2012

Molecular Implication of PP2A and Pin1 in the Alzheimer's Disease Specific Hyperphosphorylation of Tau

Por Landrieu, Isabelle, Smet-Nocca, Caroline, Amniai, Laziza, Louis, Justin Vijay, Wieruszeski, Jean-Michel, Goris, Jozef, Janssens, Veerle, Lippens, Guy
Publicado em 2011

The B″/PR72 subunit mediates Ca(2+)-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A

Por Ahn, Jung-Hyuck, Sung, Jee Young, McAvoy, Thomas, Nishi, Akinori, Janssens, Veerle, Goris, Jozef, Greengard, Paul, Nairn, Angus C.
Publicado em 2007

Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis

Por Martin, Maud, Potente, Michael, Janssens, Veerle, Vertommen, Didier, Twizere, Jean-Claude, Rider, Mark H., Goris, Jozef, Dimmeler, Stefanie, Kettmann, Richard, Dequiedt, Franck
Publicado em 2008

Suppression of Scant Identifies Endos as a Substrate of Greatwall Kinase and a Negative Regulator of Protein Phosphatase 2A in Mitosis

Por Rangone, Hélène, Wegel, Eva, Gatt, Melanie K., Yeung, Eirene, Flowers, Alexander, Debski, Janusz, Dadlez, Michal, Janssens, Veerle, Carpenter, Adelaide T. C., Glover, David M.
Publicado em 2011

An inactive protein phosphatase 2A population is associated with methylesterase and can be re-activated by the phosphotyrosyl phosphatase activator.

Por Longin, Sari, Jordens, Jan, Martens, Ellen, Stevens, Ilse, Janssens, Veerle, Rondelez, Evelien, De Baere, Ivo, Derua, Rita, Waelkens, Etienne, Goris, Jozef, Van Hoof, Christine
Publicado em 2004

Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop

Por Cobbaut, Mathias, Derua, Rita, Döppler, Heike, Lou, Hua Jane, Vandoninck, Sandy, Storz, Peter, Turk, Benjamin E., Seufferlein, Thomas, Waelkens, Etienne, Janssens, Veerle, Van Lint, Johan
Publicado no Sci Rep (2017)

Mice lacking phosphatase PP2A subunit PR61/B’δ (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3β

Por Louis, Justin V., Martens, Ellen, Borghgraef, Peter, Lambrecht, Caroline, Sents, Ward, Longin, Sari, Zwaenepoel, Karen, Pijnenborg, Robert, Landrieu, Isabelle, Lippens, Guy, Ledermann, Birgit, Götz, Jürgen, Van Leuven, Fred, Goris, Jozef, Janssens, Veerle
Publicado em 2011

Fructose-1,6-bisphosphate couples glycolytic flux to activation of Ras

Por Peeters, Ken, Van Leemputte, Frederik, Fischer, Baptiste, Bonini, Beatriz M., Quezada, Hector, Tsytlonok, Maksym, Haesen, Dorien, Vanthienen, Ward, Bernardes, Nuno, Gonzalez-Blas, Carmen Bravo, Janssens, Veerle, Tompa, Peter, Versées, Wim, Thevelein, Johan M.
Publicado no Nat Commun (2017)

Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit

Por Schott, Kerstin, Fuchs, Nina V., Derua, Rita, Mahboubi, Bijan, Schnellbächer, Esther, Seifried, Janna, Tondera, Christiane, Schmitz, Heike, Shepard, Caitlin, Brandariz-Nuñez, Alberto, Diaz-Griffero, Felipe, Reuter, Andreas, Kim, Baek, Janssens, Veerle, König, Renate
Publicado no Nat Commun (2018)

Live-cell imaging RNAi screen identifies PP2A–B55α and importin-β1 as key mitotic exit regulators in human cells

Por Schmitz, Michael H. A., Held, Michael, Janssens, Veerle, Hutchins, James R. A., Hudecz, Otto, Ivanova, Elitsa, Goris, Jozef, Trinkle-Mulcahy, Laura, Lamond, Angus I., Poser, Ina, Hyman, Anthony A., Mechtler, Karl, Peters, Jan-Michael, Gerlich, Daniel W.
Publicado em 2010

PP2A regulatory subunit Bα controls endothelial contractility and vessel lumen integrity via regulation of HDAC7

Por Martin, Maud, Geudens, Ilse, Bruyr, Jonathan, Potente, Michael, Bleuart, Anouk, Lebrun, Marielle, Simonis, Nicolas, Deroanne, Christophe, Twizere, Jean-Claude, Soubeyran, Philippe, Peixoto, Paul, Mottet, Denis, Janssens, Veerle, Hofmann, Wolf-Karsten, Claes, Filip, Carmeliet, Peter, Kettmann, Richard, Gerhardt, Holger, Dequiedt, Franck
Publicado em 2013