Molecular Implication of PP2A and Pin1 in the Alzheimer's Disease Specific Hyperphosphorylation of Tau

BACKGROUND: Tau phosphorylation and dephosphorylation regulate in a poorly understood manner its physiological role of microtubule stabilization, and equally its integration in Alzheimer disease (AD) related fibrils. A specific phospho-pattern will result from the balance between kinases and phospha...

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Main Authors: Landrieu, Isabelle, Smet-Nocca, Caroline, Amniai, Laziza, Louis, Justin Vijay, Wieruszeski, Jean-Michel, Goris, Jozef, Janssens, Veerle, Lippens, Guy
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121875/
https://ncbi.nlm.nih.gov/pubmed/21731772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021521
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