Identification of the Tau phosphorylation pattern that drives its aggregation

Determining the functional relationship between Tau phosphorylation and aggregation has proven a challenge owing to the multiple potential phosphorylation sites and their clustering in the Tau sequence. We use here in vitro kinase assays combined with NMR spectroscopy as an analytical tool to genera...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Despres, Clément, Byrne, Cillian, Qi, Haoling, Cantrelle, François-Xavier, Huvent, Isabelle, Chambraud, Béatrice, Baulieu, Etienne-Emile, Jacquot, Yves, Landrieu, Isabelle, Lippens, Guy, Smet-Nocca, Caroline
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2017
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576827/
https://ncbi.nlm.nih.gov/pubmed/28784767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708448114
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