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Tau Aggregation in Alzheimer's Disease: What Role for Phosphorylation?

The crucial role of the neuronal Tau protein in microtubule stabilization and axonal transport suggests that too little or too much Tau might lead to neuronal dysfunction. The presence of a hyper phosphorylated but non aggregated molecule as a toxic species that might sequester normal Tau is discuss...

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Detalhes bibliográficos
Main Authors: Lippens, Guy, Sillen, Alain, Landrieu, Isabelle, Amniai, Laziza, Sibille, Nathalie, Barbier, Pascale, Leroy, Arnaud, Hanoulle, Xavier, Wieruszeski, Jean-Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633703/
https://ncbi.nlm.nih.gov/pubmed/19164903
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