PP2A regulatory subunit Bα controls endothelial contractility and vessel lumen integrity via regulation of HDAC7

To supply tissues with nutrients and oxygen, the cardiovascular system forms a seamless, hierarchically branched, network of lumenized tubes. Here, we show that maintenance of patent vessel lumens requires the Bα regulatory subunit of protein phosphatase 2A (PP2A). Deficiency of Bα in zebrafish prec...

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Bibliografski detalji
Glavni autori: Martin, Maud, Geudens, Ilse, Bruyr, Jonathan, Potente, Michael, Bleuart, Anouk, Lebrun, Marielle, Simonis, Nicolas, Deroanne, Christophe, Twizere, Jean-Claude, Soubeyran, Philippe, Peixoto, Paul, Mottet, Denis, Janssens, Veerle, Hofmann, Wolf-Karsten, Claes, Filip, Carmeliet, Peter, Kettmann, Richard, Gerhardt, Holger, Dequiedt, Franck
Format: Artigo
Jezik:Inglês
Izdano: European Molecular Biology Organization 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770954/
https://ncbi.nlm.nih.gov/pubmed/23955003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.187
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