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The B″/PR72 subunit mediates Ca(2+)-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A
In dopaminoceptive neurons, dopamine- and cAMP-regulated phosphoprotein of 32 kDa (DARPP-32) plays a central role in integrating the effects of dopamine and other neurotransmitters. Phosphorylation of DARPP-32 at Thr-34 by protein kinase A results in inhibition of protein phosphatase 1 (PP1), and ph...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1887582/ https://ncbi.nlm.nih.gov/pubmed/17535922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703589104 |
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