The Talin Rod IBS2 α-Helix Interacts with the β3 Integrin Cytoplasmic Tail Membrane-proximal Helix by Establishing Charge Complementary Salt Bridges

Talin establishes a major link between integrins and actin filaments and contains two distinct integrin binding sites: one, IBS1, located in the talin head domain and involved in integrin activation and a second, IBS2, that maps to helix 50 of the talin rod domain and is essential for linking integr...

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Detalhes bibliográficos
Main Authors: Rodius, Sophie, Chaloin, Olivier, Moes, Michèle, Schaffner-Reckinger, Elisabeth, Landrieu, Isabelle, Lippens, Guy, Lin, Minghui, Zhang, Ji, Kieffer, Nelly
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259754/
https://ncbi.nlm.nih.gov/pubmed/18577523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709704200
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