Coordinated Regulation of PPARγ Expression and Activity through Control of Chromatin Structure in Adipogenesis and Obesity

Por Eeckhoute, Jérôme, Oger, Frédérik, Staels, Bart, Lefebvre, Philippe
Publicado em 2012

Distinct but complementary contributions of PPAR isotypes to energy homeostasis

Por Dubois, Vanessa, Eeckhoute, Jérôme, Lefebvre, Philippe, Staels, Bart
Publicado no J Clin Invest (2017)

The ubiquitous transcription factor CTCF promotes lineage-specific epigenomic remodeling and establishment of transcriptional networks driving cell differentiation

Por Dubois-Chevalier, Julie, Staels, Bart, Lefebvre, Philippe, Eeckhoute, Jérôme
Publicado no Nucleus (2015)

Critical role of charged residues in helix 7 of the ligand binding domain in Hepatocyte Nuclear Factor 4α dimerisation and transcriptional activity

Por Eeckhoute, Jérôme, Oxombre, Bénédicte, Formstecher, Pierre, Lefebvre, Philippe, Laine, Bernard
Publicado em 2003

A cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer

Por Eeckhoute, Jérôme, Carroll, Jason S., Geistlinger, Timothy R., Torres-Arzayus, Maria I., Brown, Myles
Publicado em 2006

Unique ERα Cistromes Control Cell Type-Specific Gene Regulation

Por Krum, Susan A., Miranda-Carboni, Gustavo A., Lupien, Mathieu, Eeckhoute, Jerome, Carroll, Jason S., Brown, Myles
Publicado em 2008

Differential Estrogen-Regulation of CXCL12 Chemokine Receptors, CXCR4 and CXCR7, Contributes to the Growth Effect of Estrogens in Breast Cancer Cells

Por Boudot, Antoine, Kerdivel, Gwenneg, Habauzit, Denis, Eeckhoute, Jerome, Le Dily, François, Flouriot, Gilles, Samson, Michel, Pakdel, Farzad
Publicado em 2011

Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers

Por Eeckhoute, Jérôme, Lupien, Mathieu, Meyer, Clifford A., Verzi, Michael P., Shivdasani, Ramesh A., Liu, X. Shirley, Brown, Myles
Publicado em 2009

Coactivator Function Defines the Active Estrogen Receptor Alpha Cistrome

Por Lupien, Mathieu, Eeckhoute, Jérôme, Meyer, Clifford A., Krum, Susan A., Rhodes, Daniel R., Liu, X. Shirley, Brown, Myles
Publicado em 2009

A dynamic CTCF chromatin binding landscape promotes DNA hydroxymethylation and transcriptional induction of adipocyte differentiation

Por Dubois-Chevalier, Julie, Oger, Frédérik, Dehondt, Hélène, Firmin, François F., Gheeraert, Céline, Staels, Bart, Lefebvre, Philippe, Eeckhoute, Jérôme
Publicado em 2014

FoxA1 translates epigenetic signatures into enhancer driven lineage-specific transcription

Por Lupien, Mathieu, Eeckhoute, Jérôme, Meyer, Clifford A., Wang, Qianben, Zhang, Yong, Li, Wei, Carroll, Jason S., Liu, X. Shirley, Brown, Myles
Publicado em 2008

Peroxisome Proliferator-activated Receptor γ Regulates Genes Involved in Insulin/Insulin-like Growth Factor Signaling and Lipid Metabolism during Adipogenesis through Functionally...

Por Oger, Frédérik, Dubois-Chevalier, Julie, Gheeraert, Céline, Avner, Stéphane, Durand, Emmanuelle, Froguel, Philippe, Salbert, Gilles, Staels, Bart, Lefebvre, Philippe, Eeckhoute, Jérôme
Publicado em 2014

Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression

Por Cowper-Sal·lari, Richard, Zhang, Xiaoyang, Wright, Jason B., Bailey, Swneke D., Cole, Michael D., Eeckhoute, Jerome, Moore, Jason H., Lupien, Mathieu
Publicado em 2012

Growth factor stimulation induces a distinct ERα cistrome underlying breast cancer endocrine resistance

Por Lupien, Mathieu, Meyer, Clifford A., Bailey, Shannon T., Eeckhoute, Jérôme, Cook, Jennifer, Westerling, Thomas, Zhang, Xiaoyang, Carroll, Jason S., Rhodes, Daniel R., Liu, X. Shirley, Brown, Myles
Publicado em 2010

Peroxisome proliferator-activated receptor ɣ activation induces 11β-hydroxysteroid dehydrogenase type 1 activity in human alternative macrophages

Por Chinetti-Gbaguidi, Giulia, Bouhlel, Mohamed Amine, Copin, Corinne, Duhem, Christian, Derudas, Bruno, Neve, Bernardette, Noel, Benoit, Eeckhoute, Jerome, Lefebvre, Philippe, Seckl, Jonathan R., Staels, Bart
Publicado em 2012

Model-based Analysis of ChIP-Seq (MACS)

Por Zhang, Yong, Liu, Tao, Meyer, Clifford A, Eeckhoute, Jérôme, Johnson, David S, Bernstein, Bradley E, Nusbaum, Chad, Myers, Richard M, Brown, Myles, Li, Wei, Liu, X Shirley
Publicado em 2008

Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers

Por Sérandour, Aurélien A., Avner, Stéphane, Percevault, Frédéric, Demay, Florence, Bizot, Maud, Lucchetti-Miganeh, Céline, Barloy-Hubler, Frédérique, Brown, Myles, Lupien, Mathieu, Métivier, Raphaël, Salbert, Gilles, Eeckhoute, Jérôme
Publicado em 2011

Dynamic Estrogen Receptor Interactomes Control Estrogen-Responsive Trefoil Factor (TFF) Locus Cell-Specific Activities

Por Quintin, Justine, Le Péron, Christine, Palierne, Gaëlle, Bizot, Maud, Cunha, Stéphanie, Sérandour, Aurélien A., Avner, Stéphane, Henry, Catherine, Percevault, Frédéric, Belaud-Rotureau, Marc-Antoine, Huet, Sébastien, Watrin, Erwan, Eeckhoute, Jérôme, Legagneux, Vincent, Salbert, Gilles, Métivier, Raphaël
Publicado em 2014

Definition of a FoxA1 Cistrome that is Crucial for G1-S Phase Cell-Cycle Transit in Castration-Resistant Prostate Cancer

Por Zhang, Chunpeng, Wang, Liguo, Wu, Dayong, Chen, Hongyan, Chen, Zhong, Thomas-Ahner, Jennifer M., Zynger, Debra L., Eeckhoute, Jérôme, Yu, Jindan, Luo, Jun, Brown, Myles, Clinton, Steven K., Nephew, Kenneth P., Huang, Tim H.-M., Li, Wei, Wang, Qianben
Publicado em 2011

Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancers

Por Sérandour, Aurélien A., Avner, Stéphane, Oger, Frédérik, Bizot, Maud, Percevault, Frédéric, Lucchetti-Miganeh, Céline, Palierne, Gaëlle, Gheeraert, Céline, Barloy-Hubler, Frédérique, Péron, Christine Le, Madigou, Thierry, Durand, Emmanuelle, Froguel, Philippe, Staels, Bart, Lefebvre, Philippe, Métivier, Raphaël, Eeckhoute, Jérôme, Salbert, Gilles
Publicado em 2012