Caricamento...
Critical role of charged residues in helix 7 of the ligand binding domain in Hepatocyte Nuclear Factor 4α dimerisation and transcriptional activity
Hepatocyte Nuclear Factor 4α (HNF4α, NR2A1) is central to hepatocyte and pancreatic β-cell functions. Along with retinoid X receptor α (RXRα), HNF4α belongs to the nuclear receptor subfamily 2 (NR2), characterised by a conserved arginyl residue and a glutamate residue insert in helix 7 (H7) of the l...
Salvato in:
Autori principali: | , , , , |
---|---|
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Oxford University Press
2003
|
Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC275546/ https://ncbi.nlm.nih.gov/pubmed/14602925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg850 |
Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|