Critical role of charged residues in helix 7 of the ligand binding domain in Hepatocyte Nuclear Factor 4α dimerisation and transcriptional activity

Những quyển sách tương tự

• The G115S mutation associated with maturity-onset diabetes of the young impairs hepatocyte nuclear factor 4α activities and introduces a PKA phosphorylation site in its DNA-binding domain
  Bằng: Oxombre, Bénédicte, et al.
  Được phát hành: (2004)
• Hepatocyte Nuclear Factor 4α enhances the Hepatocyte Nuclear Factor 1α-mediated activation of transcription
  Bằng: Eeckhoute, J., et al.
  Được phát hành: (2004)
• The DNA-binding specificity of the hepatocyte nuclear factor 3/forkhead domain is influenced by amino-acid residues adjacent to the recognition helix.
  Bằng: Overdier, D G, et al.
  Được phát hành: (1994)
• The activity of the activation function 2 of the human hepatocyte nuclear factor 4 (HNF-4alpha) is differently modulated by F domains from various origins.
  Bằng: Suaud, L, et al.
  Được phát hành: (1999)
• Nuclear receptor ligand-binding domains: reduction of helix H12 dynamics to favour crystallization
  Bằng: Nahoum, Virginie, et al.
  Được phát hành: (2008)