The ubiquitous transcription factor CTCF promotes lineage-specific epigenomic remodeling and establishment of transcriptional networks driving cell differentiation

Cell differentiation relies on tissue-specific transcription factors (TFs) that cooperate to establish unique transcriptomes and phenotypes. However, the role of ubiquitous TFs in these processes remains poorly defined. Recently, we have shown that the CCCTC-binding factor (CTCF) is required for adi...

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Veröffentlicht in:Nucleus
Hauptverfasser: Dubois-Chevalier, Julie, Staels, Bart, Lefebvre, Philippe, Eeckhoute, Jérôme
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615151/
https://ncbi.nlm.nih.gov/pubmed/25565413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2015.1004258
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