Differential Estrogen-Regulation of CXCL12 Chemokine Receptors, CXCR4 and CXCR7, Contributes to the Growth Effect of Estrogens in Breast Cancer Cells

CXCR4 and CXCR7 are the two receptors for the chemokine CXCL12, a key mediator of the growth effect of estrogens (E2) in estrogen receptor (ER)-positive breast cancers. In this study we examined E2-regulation of the CXCL12 axis components and their involvement in the growth of breast cancer cells. C...

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Detalhes bibliográficos
Main Authors: Boudot, Antoine, Kerdivel, Gwenneg, Habauzit, Denis, Eeckhoute, Jerome, Le Dily, François, Flouriot, Gilles, Samson, Michel, Pakdel, Farzad
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112227/
https://ncbi.nlm.nih.gov/pubmed/21695171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020898
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