Growth factor stimulation induces a distinct ERα cistrome underlying breast cancer endocrine resistance

Estrogen receptor α (ERα) expression in breast cancer is predictive of response to endocrine therapy; however, resistance is common in ERα-positive tumors that overexpress the growth factor receptor ERBB2. Even in the absence of estrogen, ERα can be activated by growth factors, including the epiderm...

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Detalhes bibliográficos
Main Authors: Lupien, Mathieu, Meyer, Clifford A., Bailey, Shannon T., Eeckhoute, Jérôme, Cook, Jennifer, Westerling, Thomas, Zhang, Xiaoyang, Carroll, Jason S., Rhodes, Daniel R., Liu, X. Shirley, Brown, Myles
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947773/
https://ncbi.nlm.nih.gov/pubmed/20889718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1944810
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