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PPARα blocks glucocorticoid receptor α-mediated transactivation but cooperates with the activated glucocorticoid receptor α for transrepression on NF-κB
Glucocorticoid receptor α (GRα) and peroxisome proliferator-activated receptor α (PPARα) are transcription factors with clinically important immune-modulating properties. Either receptor can inhibit cytokine gene expression, mainly through interference with nuclear factor κB (NF-κB)-driven gene expr...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678648/ https://ncbi.nlm.nih.gov/pubmed/19376972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806742106 |
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