Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1

Glucocorticoids (GCs) block inflammation via interference of the liganded glucocorticoid receptor (GR) with the activity of pro-inflammatory transcription factors NF-κB and AP-1, a mechanism known as transrepression. This mechanism is believed to involve the activity of GR monomers. Here, we explore...

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Auteurs principaux: De Bosscher, Karolien, Beck, Ilse M., Dejager, Lien, Bougarne, Nadia, Gaigneaux, Anthoula, Chateauvieux, Sébastien, Ratman, Dariusz, Bracke, Marc, Tavernier, Jan, Vanden Berghe, Wim, Libert, Claude, Diederich, Marc, Haegeman, Guy
Format: Artigo
Langue:Inglês
Publié: Springer Basel 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889831/
https://ncbi.nlm.nih.gov/pubmed/23784308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-013-1367-4
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