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Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1
Glucocorticoids (GCs) block inflammation via interference of the liganded glucocorticoid receptor (GR) with the activity of pro-inflammatory transcription factors NF-κB and AP-1, a mechanism known as transrepression. This mechanism is believed to involve the activity of GR monomers. Here, we explore...
Tallennettuna:
| Päätekijät: | , , , , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Springer Basel
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3889831/ https://ncbi.nlm.nih.gov/pubmed/23784308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-013-1367-4 |
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