Mechanisms Underlying the Functional Cooperation Between PPARα and GRα to Attenuate Inflammatory Responses

Glucocorticoids (GCs) act via the glucocorticoid receptor (NR3C1, GRα) to combat overshooting responses to infectious stimuli, including lipopolysaccharide (LPS). As such, GCs inhibit the activity of downstream effector cytokines, such as tumor necrosis factor (TNF). PPARα (NR1C1) is a nuclear recep...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Front Immunol
मुख्य लेखकों: Bougarne, Nadia, Mylka, Viacheslav, Ratman, Dariusz, Beck, Ilse M., Thommis, Jonathan, De Cauwer, Lode, Tavernier, Jan, Staels, Bart, Libert, Claude, De Bosscher, Karolien
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2019
विषय:
Immunology
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695567/
https://ncbi.nlm.nih.gov/pubmed/31447832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01769
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