The Nuclear Orphan Receptor Nur77 Is a Lipotoxicity Sensor Regulating Glucose-Induced Insulin Secretion in Pancreatic β-Cells

The NR4A orphan nuclear receptors Nur77, Nurr1, and Nor1 exert multiple cellular and metabolic functions. These transcriptional regulators are activated in response to extracellular stresses, including lipotoxic fatty acids (FA) and proinflammatory cytokines. The contribution of NR4As to β-cell path...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Endocrinol
Egile Nagusiak: Briand, Olivier, Helleboid-Chapman, Audrey, Ploton, Maheul, Hennuyer, Nathalie, Carpentier, Rodolphe, Pattou, François, Vandewalle, Brigitte, Moerman, Ericka, Gmyr, Valery, Kerr-Conte, Julie, Eeckhoute, Jérôme, Staels, Bart, Lefebvre, Philippe
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Endocrine Society 2012
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417130/
https://ncbi.nlm.nih.gov/pubmed/22301783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1317
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