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Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis.

The transcription factor Nur77 (NGFI-B), a member of the steroid nuclear receptor superfamily, is induced to a high level during T-cell receptor (TCR)-mediated apoptosis. A transgenic dominant-negative Nur77 protein can inhibit the apoptotic process accompanying negative selection in thymocytes, whi...

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Bibliografische gegevens
Hoofdauteurs: Cheng, L E, Chan, F K, Cado, D, Winoto, A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1997
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169790/
https://ncbi.nlm.nih.gov/pubmed/9155013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.8.1865
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