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Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis.
The transcription factor Nur77 (NGFI-B), a member of the steroid nuclear receptor superfamily, is induced to a high level during T-cell receptor (TCR)-mediated apoptosis. A transgenic dominant-negative Nur77 protein can inhibit the apoptotic process accompanying negative selection in thymocytes, whi...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1997
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1169790/ https://ncbi.nlm.nih.gov/pubmed/9155013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.8.1865 |
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