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Akt phosphorylates and regulates the orphan nuclear receptor Nur77
The immediate early gene NUR77 (also called NGFI-B) is required for T cell antigen receptor-mediated cell death and is induced to very high levels in immature thymocytes and T cell hybridomas undergoing apoptosis. The Akt (PKB) kinase is a key player in transduction of anti-apoptotic and proliferati...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The National Academy of Sciences
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC31113/ https://ncbi.nlm.nih.gov/pubmed/11274386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051003198 |
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