Coiled‐Coil Peptide Beacon: A Tunable Conformational Switch for Protein Detection

di Mueller, Carolin, Grossmann, Tom N.
Pubblicato in Angew Chem Int Ed Engl (2018)

Proteomimetics as protein-inspired scaffolds with defined tertiary folding patterns

di Horne, W. Seth, Grossmann, Tom N.
Pubblicato in Nat Chem (2020)

Protein–RNA interactions: structural characteristics and hotspot amino acids

di Krüger, Dennis M., Neubacher, Saskia, Grossmann, Tom N.
Pubblicato in RNA (2018)

Structure-Based Design of Inhibitors of Protein–Protein Interactions: Mimicking Peptide Binding Epitopes

di Pelay-Gimeno, Marta, Glas, Adrian, Koch, Oliver, Grossmann, Tom N
Pubblicato in Angew Chem Int Ed Engl (2015)

In Situ Cyclization of Native Proteins: Structure‐Based Design of a Bicyclic Enzyme

di Pelay‐Gimeno, Marta, Bange, Tanja, Hennig, Sven, Grossmann, Tom N.
Pubblicato in Angew Chem Int Ed Engl (2018)

In Situ Cyclization of Proteins (INCYPRO): Cross-Link Derivatization Modulates Protein Stability

di Neubacher, Saskia, Saya, Jordy M., Amore, Alessia, Grossmann, Tom N.
Pubblicato in J Org Chem (2019)

Oligonucleotides with Cationic Backbone and Their Hybridization with DNA: Interplay of Base Pairing and Electrostatic Attraction

di Schmidtgall, Boris, Kuepper, Arne, Meng, Melissa, Grossmann, Tom N., Ducho, Christian
Pubblicato in Chemistry (2017)

Increased Conformational Flexibility of a Macrocycle–Receptor Complex Contributes to Reduced Dissociation Rates

di Glas, Adrian, Wamhoff, Eike‐Christian, Krüger, Dennis M., Rademacher, Christoph, Grossmann, Tom N.
Pubblicato in Chemistry (2017)

Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides

di Cromm, Philipp M., Schaubach, Sebastian, Spiegel, Jochen, Fürstner, Alois, Grossmann, Tom N., Waldmann, Herbert
Pubblicato in Nat Commun (2016)

Adapting free energy perturbation simulations for large macrocyclic ligands: how to dissect contributions from direct binding and free ligand flexibility

di Wallraven, Kerstin, Holmelin, Fredrik L., Glas, Adrian, Hennig, Sven, Frolov, Andrey I., Grossmann, Tom N.
Pubblicato in Chem Sci (2020)

Constraining an Irregular Peptide Secondary Structure through Ring‐Closing Alkyne Metathesis

di Cromm, Philipp M., Wallraven, Kerstin, Glas, Adrian, Bier, David, Fürstner, Alois, Ottmann, Christian, Grossmann, Tom N.
Pubblicato in Chembiochem (2016)

Inhibition of oncogenic Wnt signaling through direct targeting of β-catenin

di Grossmann, Tom N., Yeh, Johannes T.-H., Bowman, Brian R., Chu, Qian, Moellering, Raymond E., Verdine, Gregory L.
Pubblicazione 2012

Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes

di Lee, Chang-Uk, Hahne, Gernot, Hanske, Jonas, Bange, Tanja, Bier, David, Rademacher, Christoph, Hennig, Sven, Grossmann, Tom N
Pubblicato in Angew Chem Int Ed Engl (2015)

Constrained Peptides with Fine‐Tuned Flexibility Inhibit NF‐Y Transcription Factor Assembly

di Jeganathan, Sadasivam, Wendt, Mathias, Kiehstaller, Sebastian, Brancaccio, Diego, Kuepper, Arne, Pospiech, Nicole, Carotenuto, Alfonso, Novellino, Ettore, Hennig, Sven, Grossmann, Tom N.
Pubblicato in Angew Chem Int Ed Engl (2019)

Structure-Based Design of Non-natural Macrocyclic Peptides That Inhibit Protein–Protein Interactions

di Krüger, Dennis M., Glas, Adrian, Bier, David, Pospiech, Nicole, Wallraven, Kerstin, Dietrich, Laura, Ottmann, Christian, Koch, Oliver, Hennig, Sven, Grossmann, Tom N.
Pubblicato in J Med Chem (2017)

Linking cytochrome P450 enzymes from Mycobacterium tuberculosis to their cognate ferredoxin partners

di Ortega Ugalde, Sandra, de Koning, Coen P., Wallraven, Kerstin, Bruyneel, Ben, Vermeulen, Nico P. E., Grossmann, Tom N., Bitter, Wilbert, Commandeur, Jan N. M., Vos, J. Chris
Pubblicato in Appl Microbiol Biotechnol (2018)

Lipidated Stapled Peptides Targeting the Acyl Binding Protein UNC119

di Cromm, Philipp M., Adihou, Hélène, Kapoor, Shobhna, Vazquez‐Chantada, Mercedes, Davey, Paul, Longmire, David, Hennes, Elisabeth, Hofer, Walter, Küchler, Philipp, Chiarparin, Elisabetta, Waldmann, Herbert, Grossmann, Tom N.
Pubblicato in Chembiochem (2019)

Macrocyclic Modalities Combining Peptide Epitopes and Natural Product Fragments

di Guéret, Stéphanie M., Thavam, Sasikala, Carbajo, Rodrigo J., Potowski, Marco, Larsson, Niklas, Dahl, Göran, Dellsén, Anita, Grossmann, Tom N., Plowright, Alleyn T., Valeur, Eric, Lemurell, Malin, Waldmann, Herbert
Pubblicato in J Am Chem Soc (2020)

Structural Analysis of the Interaction between the Bacterial Cell Division Proteins FtsQ and FtsB

di Kureisaite-Ciziene, Danguole, Varadajan, Aravindan, McLaughlin, Stephen H., Glas, Marjolein, Montón Silva, Alejandro, Luirink, Rosa, Mueller, Carolin, den Blaauwen, Tanneke, Grossmann, Tom N., Luirink, Joen, Löwe, Jan
Pubblicato in mBio (2018)

Bicyclic β‐Sheet Mimetics that Target the Transcriptional Coactivator β‐Catenin and Inhibit Wnt Signaling

di Wendt, Mathias, Bellavita, Rosa, Gerber, Alan, Efrém, Nina‐Louisa, van Ramshorst, Thirza, Pearce, Nicholas M., Davey, Paul R. J., Everard, Isabel, Vazquez‐Chantada, Mercedes, Chiarparin, Elisabetta, Grieco, Paolo, Hennig, Sven, Grossmann, Tom N.
Pubblicato in Angew Chem Int Ed Engl (2021)