Coiled‐Coil Peptide Beacon: A Tunable Conformational Switch for Protein Detection

Por Mueller, Carolin, Grossmann, Tom N.
Publicado no Angew Chem Int Ed Engl (2018)

Proteomimetics as protein-inspired scaffolds with defined tertiary folding patterns

Por Horne, W. Seth, Grossmann, Tom N.
Publicado no Nat Chem (2020)

Protein–RNA interactions: structural characteristics and hotspot amino acids

Por Krüger, Dennis M., Neubacher, Saskia, Grossmann, Tom N.
Publicado no RNA (2018)

Structure-Based Design of Inhibitors of Protein–Protein Interactions: Mimicking Peptide Binding Epitopes

Por Pelay-Gimeno, Marta, Glas, Adrian, Koch, Oliver, Grossmann, Tom N
Publicado no Angew Chem Int Ed Engl (2015)

In Situ Cyclization of Native Proteins: Structure‐Based Design of a Bicyclic Enzyme

Por Pelay‐Gimeno, Marta, Bange, Tanja, Hennig, Sven, Grossmann, Tom N.
Publicado no Angew Chem Int Ed Engl (2018)

In Situ Cyclization of Proteins (INCYPRO): Cross-Link Derivatization Modulates Protein Stability

Por Neubacher, Saskia, Saya, Jordy M., Amore, Alessia, Grossmann, Tom N.
Publicado no J Org Chem (2019)

Oligonucleotides with Cationic Backbone and Their Hybridization with DNA: Interplay of Base Pairing and Electrostatic Attraction

Por Schmidtgall, Boris, Kuepper, Arne, Meng, Melissa, Grossmann, Tom N., Ducho, Christian
Publicado no Chemistry (2017)

Increased Conformational Flexibility of a Macrocycle–Receptor Complex Contributes to Reduced Dissociation Rates

Por Glas, Adrian, Wamhoff, Eike‐Christian, Krüger, Dennis M., Rademacher, Christoph, Grossmann, Tom N.
Publicado no Chemistry (2017)

Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides

Por Cromm, Philipp M., Schaubach, Sebastian, Spiegel, Jochen, Fürstner, Alois, Grossmann, Tom N., Waldmann, Herbert
Publicado no Nat Commun (2016)

Adapting free energy perturbation simulations for large macrocyclic ligands: how to dissect contributions from direct binding and free ligand flexibility

Por Wallraven, Kerstin, Holmelin, Fredrik L., Glas, Adrian, Hennig, Sven, Frolov, Andrey I., Grossmann, Tom N.
Publicado no Chem Sci (2020)

Constraining an Irregular Peptide Secondary Structure through Ring‐Closing Alkyne Metathesis

Por Cromm, Philipp M., Wallraven, Kerstin, Glas, Adrian, Bier, David, Fürstner, Alois, Ottmann, Christian, Grossmann, Tom N.
Publicado no Chembiochem (2016)

Inhibition of oncogenic Wnt signaling through direct targeting of β-catenin

Por Grossmann, Tom N., Yeh, Johannes T.-H., Bowman, Brian R., Chu, Qian, Moellering, Raymond E., Verdine, Gregory L.
Publicado em 2012

Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes

Por Lee, Chang-Uk, Hahne, Gernot, Hanske, Jonas, Bange, Tanja, Bier, David, Rademacher, Christoph, Hennig, Sven, Grossmann, Tom N
Publicado no Angew Chem Int Ed Engl (2015)

Constrained Peptides with Fine‐Tuned Flexibility Inhibit NF‐Y Transcription Factor Assembly

Por Jeganathan, Sadasivam, Wendt, Mathias, Kiehstaller, Sebastian, Brancaccio, Diego, Kuepper, Arne, Pospiech, Nicole, Carotenuto, Alfonso, Novellino, Ettore, Hennig, Sven, Grossmann, Tom N.
Publicado no Angew Chem Int Ed Engl (2019)

Structure-Based Design of Non-natural Macrocyclic Peptides That Inhibit Protein–Protein Interactions

Por Krüger, Dennis M., Glas, Adrian, Bier, David, Pospiech, Nicole, Wallraven, Kerstin, Dietrich, Laura, Ottmann, Christian, Koch, Oliver, Hennig, Sven, Grossmann, Tom N.
Publicado no J Med Chem (2017)

Linking cytochrome P450 enzymes from Mycobacterium tuberculosis to their cognate ferredoxin partners

Por Ortega Ugalde, Sandra, de Koning, Coen P., Wallraven, Kerstin, Bruyneel, Ben, Vermeulen, Nico P. E., Grossmann, Tom N., Bitter, Wilbert, Commandeur, Jan N. M., Vos, J. Chris
Publicado no Appl Microbiol Biotechnol (2018)

Lipidated Stapled Peptides Targeting the Acyl Binding Protein UNC119

Por Cromm, Philipp M., Adihou, Hélène, Kapoor, Shobhna, Vazquez‐Chantada, Mercedes, Davey, Paul, Longmire, David, Hennes, Elisabeth, Hofer, Walter, Küchler, Philipp, Chiarparin, Elisabetta, Waldmann, Herbert, Grossmann, Tom N.
Publicado no Chembiochem (2019)

Macrocyclic Modalities Combining Peptide Epitopes and Natural Product Fragments

Por Guéret, Stéphanie M., Thavam, Sasikala, Carbajo, Rodrigo J., Potowski, Marco, Larsson, Niklas, Dahl, Göran, Dellsén, Anita, Grossmann, Tom N., Plowright, Alleyn T., Valeur, Eric, Lemurell, Malin, Waldmann, Herbert
Publicado no J Am Chem Soc (2020)

Structural Analysis of the Interaction between the Bacterial Cell Division Proteins FtsQ and FtsB

Por Kureisaite-Ciziene, Danguole, Varadajan, Aravindan, McLaughlin, Stephen H., Glas, Marjolein, Montón Silva, Alejandro, Luirink, Rosa, Mueller, Carolin, den Blaauwen, Tanneke, Grossmann, Tom N., Luirink, Joen, Löwe, Jan
Publicado no mBio (2018)

Plant cysteine oxidases are dioxygenases that directly enable arginyl transferase-catalysed arginylation of N-end rule targets

Por White, Mark D., Klecker, Maria, Hopkinson, Richard J., Weits, Daan A., Mueller, Carolin, Naumann, Christin, O'Neill, Rebecca, Wickens, James, Yang, Jiayu, Brooks-Bartlett, Jonathan C., Garman, Elspeth F., Grossmann, Tom N., Dissmeyer, Nico, Flashman, Emily
Publicado no Nat Commun (2017)