Bicyclic β‐Sheet Mimetics that Target the Transcriptional Coactivator β‐Catenin and Inhibit Wnt Signaling

Protein complexes are defined by the three‐dimensional structure of participating binding partners. Knowledge about these structures can facilitate the design of peptidomimetics which have been applied for example, as inhibitors of protein–protein interactions (PPIs). Even though β‐sheets participat...

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Publicado en:Angew Chem Int Ed Engl
Autores principales: Wendt, Mathias, Bellavita, Rosa, Gerber, Alan, Efrém, Nina‐Louisa, van Ramshorst, Thirza, Pearce, Nicholas M., Davey, Paul R. J., Everard, Isabel, Vazquez‐Chantada, Mercedes, Chiarparin, Elisabetta, Grieco, Paolo, Hennig, Sven, Grossmann, Tom N.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252567/
https://ncbi.nlm.nih.gov/pubmed/33783110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202102082
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