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Effects of turn residues in directing the formation of the β-sheet and in the stability of the β-sheet

The designed peptide (denoted 20-mer, sequence VFITS(D)PGKTYTEV(D)PGOKILQ) has been shown to form a three-strand antiparallel β-sheet. It is generally believed that the (D)Pro-Gly segment has the propensity to adopt a type II′ β-turn, thereby promoting the formation of this β-sheet. Here, we replace...

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Detalhes bibliográficos
Main Authors: Chen, Pei-Yeh, Lin, Chih-Kai, Lee, Chung-Tien, Jan, Howard, Chan, Sunney I.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253197/
https://ncbi.nlm.nih.gov/pubmed/11514670
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