Evaluating β-turn mimics as β-sheet folding nucleators

β-Turns are common conformations that enable proteins to adopt globular structures, and their formation is often rate limiting for folding. β-Turn mimics, molecules that replace the i + 1 and i + 2 amino acid residues of a β-turn, are envisioned to act as folding nucleators by preorganizing the pend...

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Detalhes bibliográficos
Main Authors: Fuller, Amelia A., Du, Deguo, Liu, Feng, Davoren, Jennifer E., Bhabha, Gira, Kroon, Gerard, Case, David A., Dyson, H. Jane, Powers, Evan T., Wipf, Peter, Gruebele, Martin, Kelly, Jeffery W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708776/
https://ncbi.nlm.nih.gov/pubmed/19541614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813012106
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