Coiled‐Coil Peptide Beacon: A Tunable Conformational Switch for Protein Detection

מאת Mueller, Carolin, Grossmann, Tom N.
הוצא לאור ב Angew Chem Int Ed Engl (2018)

Proteomimetics as protein-inspired scaffolds with defined tertiary folding patterns

מאת Horne, W. Seth, Grossmann, Tom N.
הוצא לאור ב Nat Chem (2020)

Protein–RNA interactions: structural characteristics and hotspot amino acids

מאת Krüger, Dennis M., Neubacher, Saskia, Grossmann, Tom N.
הוצא לאור ב RNA (2018)

Structure-Based Design of Inhibitors of Protein–Protein Interactions: Mimicking Peptide Binding Epitopes

מאת Pelay-Gimeno, Marta, Glas, Adrian, Koch, Oliver, Grossmann, Tom N
הוצא לאור ב Angew Chem Int Ed Engl (2015)

In Situ Cyclization of Native Proteins: Structure‐Based Design of a Bicyclic Enzyme

מאת Pelay‐Gimeno, Marta, Bange, Tanja, Hennig, Sven, Grossmann, Tom N.
הוצא לאור ב Angew Chem Int Ed Engl (2018)

In Situ Cyclization of Proteins (INCYPRO): Cross-Link Derivatization Modulates Protein Stability

מאת Neubacher, Saskia, Saya, Jordy M., Amore, Alessia, Grossmann, Tom N.
הוצא לאור ב J Org Chem (2019)

Oligonucleotides with Cationic Backbone and Their Hybridization with DNA: Interplay of Base Pairing and Electrostatic Attraction

מאת Schmidtgall, Boris, Kuepper, Arne, Meng, Melissa, Grossmann, Tom N., Ducho, Christian
הוצא לאור ב Chemistry (2017)

Increased Conformational Flexibility of a Macrocycle–Receptor Complex Contributes to Reduced Dissociation Rates

מאת Glas, Adrian, Wamhoff, Eike‐Christian, Krüger, Dennis M., Rademacher, Christoph, Grossmann, Tom N.
הוצא לאור ב Chemistry (2017)

Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides

מאת Cromm, Philipp M., Schaubach, Sebastian, Spiegel, Jochen, Fürstner, Alois, Grossmann, Tom N., Waldmann, Herbert
הוצא לאור ב Nat Commun (2016)

Adapting free energy perturbation simulations for large macrocyclic ligands: how to dissect contributions from direct binding and free ligand flexibility

מאת Wallraven, Kerstin, Holmelin, Fredrik L., Glas, Adrian, Hennig, Sven, Frolov, Andrey I., Grossmann, Tom N.
הוצא לאור ב Chem Sci (2020)

Constraining an Irregular Peptide Secondary Structure through Ring‐Closing Alkyne Metathesis

מאת Cromm, Philipp M., Wallraven, Kerstin, Glas, Adrian, Bier, David, Fürstner, Alois, Ottmann, Christian, Grossmann, Tom N.
הוצא לאור ב Chembiochem (2016)

Inhibition of oncogenic Wnt signaling through direct targeting of β-catenin

מאת Grossmann, Tom N., Yeh, Johannes T.-H., Bowman, Brian R., Chu, Qian, Moellering, Raymond E., Verdine, Gregory L.
יצא לאור 2012

Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes

מאת Lee, Chang-Uk, Hahne, Gernot, Hanske, Jonas, Bange, Tanja, Bier, David, Rademacher, Christoph, Hennig, Sven, Grossmann, Tom N
הוצא לאור ב Angew Chem Int Ed Engl (2015)

Constrained Peptides with Fine‐Tuned Flexibility Inhibit NF‐Y Transcription Factor Assembly

מאת Jeganathan, Sadasivam, Wendt, Mathias, Kiehstaller, Sebastian, Brancaccio, Diego, Kuepper, Arne, Pospiech, Nicole, Carotenuto, Alfonso, Novellino, Ettore, Hennig, Sven, Grossmann, Tom N.
הוצא לאור ב Angew Chem Int Ed Engl (2019)

Structure-Based Design of Non-natural Macrocyclic Peptides That Inhibit Protein–Protein Interactions

מאת Krüger, Dennis M., Glas, Adrian, Bier, David, Pospiech, Nicole, Wallraven, Kerstin, Dietrich, Laura, Ottmann, Christian, Koch, Oliver, Hennig, Sven, Grossmann, Tom N.
הוצא לאור ב J Med Chem (2017)

Linking cytochrome P450 enzymes from Mycobacterium tuberculosis to their cognate ferredoxin partners

מאת Ortega Ugalde, Sandra, de Koning, Coen P., Wallraven, Kerstin, Bruyneel, Ben, Vermeulen, Nico P. E., Grossmann, Tom N., Bitter, Wilbert, Commandeur, Jan N. M., Vos, J. Chris
הוצא לאור ב Appl Microbiol Biotechnol (2018)

Lipidated Stapled Peptides Targeting the Acyl Binding Protein UNC119

מאת Cromm, Philipp M., Adihou, Hélène, Kapoor, Shobhna, Vazquez‐Chantada, Mercedes, Davey, Paul, Longmire, David, Hennes, Elisabeth, Hofer, Walter, Küchler, Philipp, Chiarparin, Elisabetta, Waldmann, Herbert, Grossmann, Tom N.
הוצא לאור ב Chembiochem (2019)

Macrocyclic Modalities Combining Peptide Epitopes and Natural Product Fragments

מאת Guéret, Stéphanie M., Thavam, Sasikala, Carbajo, Rodrigo J., Potowski, Marco, Larsson, Niklas, Dahl, Göran, Dellsén, Anita, Grossmann, Tom N., Plowright, Alleyn T., Valeur, Eric, Lemurell, Malin, Waldmann, Herbert
הוצא לאור ב J Am Chem Soc (2020)

Structural Analysis of the Interaction between the Bacterial Cell Division Proteins FtsQ and FtsB

מאת Kureisaite-Ciziene, Danguole, Varadajan, Aravindan, McLaughlin, Stephen H., Glas, Marjolein, Montón Silva, Alejandro, Luirink, Rosa, Mueller, Carolin, den Blaauwen, Tanneke, Grossmann, Tom N., Luirink, Joen, Löwe, Jan
הוצא לאור ב mBio (2018)

Bicyclic β‐Sheet Mimetics that Target the Transcriptional Coactivator β‐Catenin and Inhibit Wnt Signaling

מאת Wendt, Mathias, Bellavita, Rosa, Gerber, Alan, Efrém, Nina‐Louisa, van Ramshorst, Thirza, Pearce, Nicholas M., Davey, Paul R. J., Everard, Isabel, Vazquez‐Chantada, Mercedes, Chiarparin, Elisabetta, Grieco, Paolo, Hennig, Sven, Grossmann, Tom N.
הוצא לאור ב Angew Chem Int Ed Engl (2021)