Coiled‐Coil Peptide Beacon: A Tunable Conformational Switch for Protein Detection

per Mueller, Carolin, Grossmann, Tom N.
Publicat a Angew Chem Int Ed Engl (2018)

Proteomimetics as protein-inspired scaffolds with defined tertiary folding patterns

per Horne, W. Seth, Grossmann, Tom N.
Publicat a Nat Chem (2020)

Protein–RNA interactions: structural characteristics and hotspot amino acids

per Krüger, Dennis M., Neubacher, Saskia, Grossmann, Tom N.
Publicat a RNA (2018)

Structure-Based Design of Inhibitors of Protein–Protein Interactions: Mimicking Peptide Binding Epitopes

per Pelay-Gimeno, Marta, Glas, Adrian, Koch, Oliver, Grossmann, Tom N
Publicat a Angew Chem Int Ed Engl (2015)

In Situ Cyclization of Native Proteins: Structure‐Based Design of a Bicyclic Enzyme

per Pelay‐Gimeno, Marta, Bange, Tanja, Hennig, Sven, Grossmann, Tom N.
Publicat a Angew Chem Int Ed Engl (2018)

In Situ Cyclization of Proteins (INCYPRO): Cross-Link Derivatization Modulates Protein Stability

per Neubacher, Saskia, Saya, Jordy M., Amore, Alessia, Grossmann, Tom N.
Publicat a J Org Chem (2019)

Oligonucleotides with Cationic Backbone and Their Hybridization with DNA: Interplay of Base Pairing and Electrostatic Attraction

per Schmidtgall, Boris, Kuepper, Arne, Meng, Melissa, Grossmann, Tom N., Ducho, Christian
Publicat a Chemistry (2017)

Increased Conformational Flexibility of a Macrocycle–Receptor Complex Contributes to Reduced Dissociation Rates

per Glas, Adrian, Wamhoff, Eike‐Christian, Krüger, Dennis M., Rademacher, Christoph, Grossmann, Tom N.
Publicat a Chemistry (2017)

Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides

per Cromm, Philipp M., Schaubach, Sebastian, Spiegel, Jochen, Fürstner, Alois, Grossmann, Tom N., Waldmann, Herbert
Publicat a Nat Commun (2016)

Adapting free energy perturbation simulations for large macrocyclic ligands: how to dissect contributions from direct binding and free ligand flexibility

per Wallraven, Kerstin, Holmelin, Fredrik L., Glas, Adrian, Hennig, Sven, Frolov, Andrey I., Grossmann, Tom N.
Publicat a Chem Sci (2020)

Constraining an Irregular Peptide Secondary Structure through Ring‐Closing Alkyne Metathesis

per Cromm, Philipp M., Wallraven, Kerstin, Glas, Adrian, Bier, David, Fürstner, Alois, Ottmann, Christian, Grossmann, Tom N.
Publicat a Chembiochem (2016)

Inhibition of oncogenic Wnt signaling through direct targeting of β-catenin

per Grossmann, Tom N., Yeh, Johannes T.-H., Bowman, Brian R., Chu, Qian, Moellering, Raymond E., Verdine, Gregory L.
Publicat 2012

Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes

per Lee, Chang-Uk, Hahne, Gernot, Hanske, Jonas, Bange, Tanja, Bier, David, Rademacher, Christoph, Hennig, Sven, Grossmann, Tom N
Publicat a Angew Chem Int Ed Engl (2015)

Constrained Peptides with Fine‐Tuned Flexibility Inhibit NF‐Y Transcription Factor Assembly

per Jeganathan, Sadasivam, Wendt, Mathias, Kiehstaller, Sebastian, Brancaccio, Diego, Kuepper, Arne, Pospiech, Nicole, Carotenuto, Alfonso, Novellino, Ettore, Hennig, Sven, Grossmann, Tom N.
Publicat a Angew Chem Int Ed Engl (2019)

Structure-Based Design of Non-natural Macrocyclic Peptides That Inhibit Protein–Protein Interactions

per Krüger, Dennis M., Glas, Adrian, Bier, David, Pospiech, Nicole, Wallraven, Kerstin, Dietrich, Laura, Ottmann, Christian, Koch, Oliver, Hennig, Sven, Grossmann, Tom N.
Publicat a J Med Chem (2017)

Linking cytochrome P450 enzymes from Mycobacterium tuberculosis to their cognate ferredoxin partners

per Ortega Ugalde, Sandra, de Koning, Coen P., Wallraven, Kerstin, Bruyneel, Ben, Vermeulen, Nico P. E., Grossmann, Tom N., Bitter, Wilbert, Commandeur, Jan N. M., Vos, J. Chris
Publicat a Appl Microbiol Biotechnol (2018)

Lipidated Stapled Peptides Targeting the Acyl Binding Protein UNC119

per Cromm, Philipp M., Adihou, Hélène, Kapoor, Shobhna, Vazquez‐Chantada, Mercedes, Davey, Paul, Longmire, David, Hennes, Elisabeth, Hofer, Walter, Küchler, Philipp, Chiarparin, Elisabetta, Waldmann, Herbert, Grossmann, Tom N.
Publicat a Chembiochem (2019)

Macrocyclic Modalities Combining Peptide Epitopes and Natural Product Fragments

per Guéret, Stéphanie M., Thavam, Sasikala, Carbajo, Rodrigo J., Potowski, Marco, Larsson, Niklas, Dahl, Göran, Dellsén, Anita, Grossmann, Tom N., Plowright, Alleyn T., Valeur, Eric, Lemurell, Malin, Waldmann, Herbert
Publicat a J Am Chem Soc (2020)

Structural Analysis of the Interaction between the Bacterial Cell Division Proteins FtsQ and FtsB

per Kureisaite-Ciziene, Danguole, Varadajan, Aravindan, McLaughlin, Stephen H., Glas, Marjolein, Montón Silva, Alejandro, Luirink, Rosa, Mueller, Carolin, den Blaauwen, Tanneke, Grossmann, Tom N., Luirink, Joen, Löwe, Jan
Publicat a mBio (2018)

Bicyclic β‐Sheet Mimetics that Target the Transcriptional Coactivator β‐Catenin and Inhibit Wnt Signaling

per Wendt, Mathias, Bellavita, Rosa, Gerber, Alan, Efrém, Nina‐Louisa, van Ramshorst, Thirza, Pearce, Nicholas M., Davey, Paul R. J., Everard, Isabel, Vazquez‐Chantada, Mercedes, Chiarparin, Elisabetta, Grieco, Paolo, Hennig, Sven, Grossmann, Tom N.
Publicat a Angew Chem Int Ed Engl (2021)