Loss of compensatory pro-survival and anti-apoptotic modulator, IKKε, sensitizes ovarian cancer cells to CHEK1 loss through an increased level of p21

Por Kim, Marianne K., Min, Dong J., Wright, George, Goldlust, Ian, Annunziata, Christina M.
Publicado no Oncotarget (2014)

Modelling of the cancer cell cycle as a tool for rational drug development: A systems pharmacology approach to cyclotherapy

Por Jackson, Robert C., Di Veroli, Giovanni Y., Koh, Siang-Boon, Goldlust, Ian, Richards, Frances M., Jodrell, Duncan I.
Publicado no PLoS Comput Biol (2017)

An automated fitting procedure and software for dose-response curves with multiphasic features

Por Veroli, Giovanni Y. Di, Fornari, Chiara, Goldlust, Ian, Mills, Graham, Koh, Siang Boon, Bramhall, Jo L, Richards, Frances M., Jodrell, Duncan I.
Publicado no Sci Rep (2015)

Say No to DMSO: Dimethylsulfoxide Inactivates Cisplatin, Carboplatin and Other Platinum Complexes

Por Hall, Matthew D., Telma, Katherine A., Chang, Ki-Eun, Lee, Tobie D., Madigan, James P., Lloyd, John R., Goldlust, Ian S., Hoeschele, James D., Gottesman, Michael M.
Publicado em 2014

Large-scale pharmacological profiling of 3D tumor models of cancer cells

Por Mathews Griner, Lesley A, Zhang, Xiaohu, Guha, Rajarshi, McKnight, Crystal, Goldlust, Ian S, Lal-Nag, Madhu, Wilson, Kelli, Michael, Sam, Titus, Steve, Shinn, Paul, Thomas, Craig J, Ferrer, Marc
Publicado no Cell Death Dis (2016)

Synthetic Riboswitches That Induce Gene Expression in Diverse Bacterial Species

Por Topp, Shana, Reynoso, Colleen M. K., Seeliger, Jessica C., Goldlust, Ian S., Desai, Shawn K., Murat, Dorothée, Shen, Aimee, Puri, Aaron W., Komeili, Arash, Bertozzi, Carolyn R., Scott, June R., Gallivan, Justin P.
Publicado em 2010

Synthetic Riboswitches That Induce Gene Expression in Diverse Bacterial Species

Por Topp, Shana, Reynoso, Colleen M. K., Seeliger, Jessica C., Goldlust, Ian S., Desai, Shawn K., Murat, Dorothée, Shen, Aimee, Puri, Aaron W., Komeili, Arash, Bertozzi, Carolyn R., Scott, June R., Gallivan, Justin P.
Publicado em 2011

mQC: A Heuristic Quality-Control Metric for High-Throughput Drug Combination Screening

Por Chen, Lu, Wilson, Kelli, Goldlust, Ian, Mott, Bryan T., Eastman, Richard, Davis, Mindy I., Zhang, Xiaohu, McKnight, Crystal, Klumpp-Thomas, Carleen, Shinn, Paul, Simmons, John, Gormally, Mike, Michael, Sam, Thomas, Craig J., Ferrer, Marc, Guha, Rajarshi
Publicado no Sci Rep (2016)

Drugs Targeting Tumor-Initiating Cells Prolong Survival in a Post-Surgery, Post-Chemotherapy Ovarian Cancer Relapse Model

Por Harrington, Brittney S., Ozaki, Michelle K., Caminear, Michael W., Hernandez, Lidia F., Jordan, Elizabeth, Kalinowski, Nicholas J., Goldlust, Ian S., Guha, Rajarshi, Ferrer, Marc, Thomas, Craig, Shetty, Jyoti, Tran, Bao, Wong, Nathan, House, Carrie D., Annunziata, Christina M.
Publicado no Cancers (Basel) (2020)

Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency

Por Wang, Tao, Wu, Hao, Li, Yujing, Szulwach, Keith E., Lin, Li, Li, Xuekun, Chen, I-Ping, Goldlust, Ian S., Chamberlain, Stormy J., Dodd, Ann, Gong, He, Ananiev, Gene, Han, Ji Woong, Yoon, Young-sup, Rudd, M. Katharine, Yu, Miao, Song, Chun-Xiao, He, Chuan, Chang, Qiang, Warren, Stephen T., Jin, Peng
Publicado em 2013

Mouse model implicates GNB3 duplication in a childhood obesity syndrome

Por Goldlust, Ian S., Hermetz, Karen E., Catalano, Lisa M., Barfield, Richard T., Cozad, Rebecca, Wynn, Grace, Ozdemir, Alev Cagla, Conneely, Karen N., Mulle, Jennifer G., Dharamrup, Shikha, Hegde, Madhuri R., Kim, Katherine H., Angle, Brad, Colley, Alison, Webb, Amy E., Thorland, Erik C., Ellison, Jay W., Rosenfeld, Jill A., Ballif, Blake C., Shaffer, Lisa G., Demmer, Laurie A., Rudd, M. Katharine, Searle, Beverly A, Wynn, Sarah L.
Publicado em 2013

Type-1-cytokines synergize with oncogene inhibition to induce tumor growth arrest

Por Acquavella, Nicolas, Clever, David, Yu, Zhiya, Roelke-Parker, Melody, Palmer, Douglas C., Xi, Liqiang, Pflicke, Holger, Ji, Yun, Gros, Alena, Hanada, Ken-ichi, Goldlust, Ian S., Mehta, Gautam U., Klebanoff, Christopher A., Crompton, Joseph G., Sukumar, Madhusudhanan, Morrow, James J., Franco, Zulmarie, Gattinoni, Luca, Liu, Hui, Wang, Ena, Marincola, Francesco, Stroncek, David F., Lee, Chyi-Chia R., Raffeld, Mark, Bosenberg, Marcus W., Roychoudhuri, Rahul, Restifo, Nicholas P.
Publicado no Cancer Immunol Res (2014)

High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells

Por Mathews Griner, Lesley A., Guha, Rajarshi, Shinn, Paul, Young, Ryan M., Keller, Jonathan M., Liu, Dongbo, Goldlust, Ian S., Yasgar, Adam, McKnight, Crystal, Boxer, Matthew B., Duveau, Damien Y., Jiang, Jian-Kang, Michael, Sam, Mierzwa, Tim, Huang, Wenwei, Walsh, Martin J., Mott, Bryan T., Patel, Paresma, Leister, William, Maloney, David J., Leclair, Christopher A., Rai, Ganesha, Jadhav, Ajit, Peyser, Brian D., Austin, Christopher P., Martin, Scott E., Simeonov, Anton, Ferrer, Marc, Staudt, Louis M., Thomas, Craig J.
Publicado em 2014