Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency

Mammalian somatic cells can be directly reprogrammed into induced pluripotent stem cells (iPSCs) by introducing defined sets of transcription factors. Somatic cell reprogramming involves epigenomic reconfiguration, conferring iPSCs with characteristics similar to embryonic stem cells (ESCs). Human E...

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Hlavní autoři: Wang, Tao, Wu, Hao, Li, Yujing, Szulwach, Keith E., Lin, Li, Li, Xuekun, Chen, I-Ping, Goldlust, Ian S., Chamberlain, Stormy J., Dodd, Ann, Gong, He, Ananiev, Gene, Han, Ji Woong, Yoon, Young-sup, Rudd, M. Katharine, Yu, Miao, Song, Chun-Xiao, He, Chuan, Chang, Qiang, Warren, Stephen T., Jin, Peng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998089/
https://ncbi.nlm.nih.gov/pubmed/23685628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2748
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